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CAEEL:DPOLQ

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) polq-1 (ECO:0000312 with WormBase:W03A3.2)
Protein Name(s) DNA polymerase theta (ECO:0000250 with UniProtKB:O75417)
External Links
UniProt A0FLQ6
EMBL FO081687
FO081686
RefSeq NP_498250.3
UniGene Cel.9944
ProteinModelPortal A0FLQ6
STRING 6239.W03A3.2
PaxDb A0FLQ6
PRIDE A0FLQ6
EnsemblMetazoa [example_ID W03A3.2]
GeneID 175810
KEGG cel:CELE_W03A3.2
UCSC W03A3.2
CTD 175810
WormBase W03A3.2
eggNOG KOG0950
COG0749
COG1204
GeneTree ENSGT00640000091272
InParanoid A0FLQ6
KO K02349
OMA MENCAKL
OrthoDB EOG75QR31
PRO PR:A0FLQ6
Proteomes UP000001940
GO GO:0005634
GO:0005524
GO:0003677
GO:0003887
GO:0006287
GO:0006261
Gene3D 3.40.50.300
InterPro IPR011545
IPR019760
IPR001098
IPR002298
IPR014001
IPR001650
IPR027417
Pfam PF00270
PF00476
PF00271
PRINTS PR00868
SMART SM00487
SM00490
SM00482
SUPFAM SSF52540
PROSITE PS00447
PS51192
PS51194

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006287

base-excision repair, gap-filling

PMID:21917855[1]

ECO:0000315

P

Figure 5: BER activity from the polq-1 mutation extract lower compared to the BER activity in the wild-type extract prepared in parallel

complete
CACAO 6839

involved_in

GO:0071479

cellular response to ionizing radiation

PMID:29463814[2]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:G5EGA3

P

Seeded From UniProt

complete

involved_in

GO:0006287

base-excision repair, gap-filling

PMID:21917855[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006261

DNA-dependent DNA replication

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10746
PANTHER:PTN000015249

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10746
PANTHER:PTN000015249

C

Seeded From UniProt

complete

involved_in

GO:0071897

DNA biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003887

P

Seeded From UniProt

complete

involved_in

GO:0071897

DNA biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003887

P

Seeded From UniProt

complete

involved_in

GO:0071897

DNA biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003887

P

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011545

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001098

F

Seeded From UniProt

complete

enables

GO:0003887

DNA-directed DNA polymerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001098
InterPro:IPR002298
InterPro:IPR019760

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011545

F

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001098
InterPro:IPR019760

P

Seeded From UniProt

complete

involved_in

GO:0006261

DNA-dependent DNA replication

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002298

P

Seeded From UniProt

complete

enables

GO:0003887

DNA-directed DNA polymerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.7.7

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0016779

nucleotidyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0548

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0003887

DNA-directed DNA polymerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0239

F

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Asagoshi, K et al. (2012) Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase β. Nucleic Acids Res. 40 670-81 PubMed GONUTS page
  2. Hong, Y et al. (2018) LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis. Nat Commun 9 728 PubMed GONUTS page
  3. 3.0 3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page