CAEEL:CHE1

Species (Taxon ID)	Caenorhabditis elegans. (6239)
Gene Name(s)	che-1
Protein Name(s)	Transcription factor che-1 Abnormal chemotaxis protein 1
External Links
UniProt	Q966L8
EMBL	FO080958
RefSeq	NP_001076597.1
UniGene	Cel.23650
ProteinModelPortal	Q966L8
SMR	Q966L8
GeneID	183847
KEGG	cel:CELE_C55B7.12
UCSC	C55B7.12b
CTD	183847
WormBase	C55B7.12a
eggNOG	COG5048
HOGENOM	HOG000019805
InParanoid	Q966L8
KO	K09214
OMA	MSYHYQM
OrthoDB	EOG7SXW38
SignaLink	Q966L8
NextBio	922572
Proteomes	UP000001940
ExpressionAtlas	Q966L8
GO	GO:0005634 GO:0046872 GO:0000977 GO:0043565 GO:0006935 GO:0030182 GO:0045944 GO:0050920 GO:0006351
Gene3D	3.30.160.60
InterPro	IPR007087 IPR015880 IPR013087
SMART	SM00355
PROSITE	PS00028 PS50157

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0007635	chemosensory behavior	PMID:20837997^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(CHEBI:26710) occurs_in:(WBbt:0005663)	Seeded From UniProt	complete
involved_in	GO:1902074	response to salt	PMID:20837997^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(CHEBI:26710) occurs_in:(WBbt:0005663)	Seeded From UniProt	complete
involved_in	GO:0050921	positive regulation of chemotaxis	PMID:20837997^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(CHEBI:26710) occurs_in:(WBbt:0005663)	Seeded From UniProt	complete
involved_in	GO:0007635	chemosensory behavior	PMID:23664973^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	PMID:23664973^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010446	response to alkaline pH	PMID:23664973^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010035	response to inorganic substance	PMID:19523832^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(CHEBI:47265) part_of:(GO:1902074)\|has_input(CHEBI:16382) part_of:(GO:1902074)	Seeded From UniProt	complete
involved_in	GO:0010226	response to lithium ion	PMID:19523832^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:1902074)	Seeded From UniProt	complete
involved_in	GO:0032026	response to magnesium ion	PMID:19523832^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:1902074)	Seeded From UniProt	complete
involved_in	GO:0007635	chemosensory behavior	PMID:19523832^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	happens_during:(GO:0032026)\|happens_during:(GO:0010226)\|happens_during:(GO:0010035)\|happens_during:(GO:1904640)	Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	PMID:19523832^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	happens_during:(GO:0032026)\|happens_during:(GO:0010226)\|happens_during:(GO:0010035)\|happens_during:(GO:1904640)	Seeded From UniProt	complete
involved_in	GO:1904640	response to methionine	PMID:19523832^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1902074	response to salt	PMID:19523832^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	PMID:19060335^[4]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(WB:WBGene00000457)\|has_direct_input:(WB:WBGene00001532)	Seeded From UniProt	complete
involved_in	GO:0050920	regulation of chemotaxis	PMID:12588839^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	WB:WBVar00095117 WB:WBVar00095122	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:12588839^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	WB:WBVar00095117	P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:19189954^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:12588839^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	WB:WBVar00095117	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:12588839^[5]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P13360	C		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0001180 PANTHER:PTN000694458 WB:WBGene00000483	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0259789 PANTHER:PTN000694458 UniProtKB:Q05516	P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000694458 UniProtKB:Q05516 UniProtKB:Q7Z4V0	P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0001180 FB:FBgn0259789 PANTHER:PTN000694458 WB:WBGene00000483	F		Seeded From UniProt	complete
colocalizes_with	GO:0005654	nucleoplasm	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0259789 PANTHER:PTN000694458 UniProtKB:Q7Z4V0	C		Seeded From UniProt	complete
colocalizes_with	GO:0005634	nucleus	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0034240 MGI:MGI:1921783 MGI:MGI:2665174 PANTHER:PTN000694458 RGD:727921 UniProtKB:Q05516 UniProtKB:Q7Z4V0 ZFIN:ZDB-GENE-100923-1	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0001180 MGI:MGI:2665174 PANTHER:PTN000694458 RGD:727921 UniProtKB:Q7Z4V0	F		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013087	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0145	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Adachi, T et al. (2010) Reversal of salt preference is directed by the insulin/PI3K and Gq/PKC signaling in Caenorhabditis elegans. Genetics 186 1309-19 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Murayama, T et al. (2013) Environmental alkalinity sensing mediated by the transmembrane guanylyl cyclase GCY-14 in C. elegans. Curr. Biol. 23 1007-12 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Ortiz, CO et al. (2009) Lateralized gustatory behavior of C. elegans is controlled by specific receptor-type guanylyl cyclases. Curr. Biol. 19 996-1004 PubMed GONUTS page
↑ Etchberger, JF et al. (2009) Cis-regulatory mechanisms of left/right asymmetric neuron-subtype specification in C. elegans. Development 136 147-60 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 Uchida, O et al. (2003) The C. elegans che-1 gene encodes a zinc finger transcription factor required for specification of the ASE chemosensory neurons. Development 130 1215-24 PubMed GONUTS page
↑ O'Meara, MM et al. (2009) Cis-regulatory mutations in the Caenorhabditis elegans homeobox gene locus cog-1 affect neuronal development. Genetics 181 1679-86 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 ^7.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:20837997-1] 1.0 ^1.1 ^1.2 Adachi, T et al. (2010) Reversal of salt preference is directed by the insulin/PI3K and Gq/PKC signaling in Caenorhabditis elegans. Genetics 186 1309-19 PubMed GONUTS page

[PMID:23664973-2] 2.0 ^2.1 ^2.2 Murayama, T et al. (2013) Environmental alkalinity sensing mediated by the transmembrane guanylyl cyclase GCY-14 in C. elegans. Curr. Biol. 23 1007-12 PubMed GONUTS page

[PMID:19523832-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Ortiz, CO et al. (2009) Lateralized gustatory behavior of C. elegans is controlled by specific receptor-type guanylyl cyclases. Curr. Biol. 19 996-1004 PubMed GONUTS page

[PMID:19060335-4] Etchberger, JF et al. (2009) Cis-regulatory mechanisms of left/right asymmetric neuron-subtype specification in C. elegans. Development 136 147-60 PubMed GONUTS page

[PMID:12588839-5] 5.0 ^5.1 ^5.2 ^5.3 Uchida, O et al. (2003) The C. elegans che-1 gene encodes a zinc finger transcription factor required for specification of the ASE chemosensory neurons. Development 130 1215-24 PubMed GONUTS page

[PMID:19189954-6] O'Meara, MM et al. (2009) Cis-regulatory mutations in the Caenorhabditis elegans homeobox gene locus cog-1 affect neuronal development. Genetics 181 1679-86 PubMed GONUTS page

[PMID:21873635-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 ^7.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CAEEL:CHE1

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