BPE15:Q858G8

Species (Taxon ID)	Salmonella phage epsilon15. (215158)
Gene Name(s)	No Information Provided.
Protein Name(s)	Major capsid protein (ECO:0000313 with EMBL:AAO06070.1)
External Links
UniProt	Q858G8
EMBL	AY150271
RefSeq	NP_848215.1
PDB	3J40
PDBsum	3J40
DIP	DIP-59827N
GeneID	2641870
KEGG	vg:2641870
OrthoDB	VOG090002H2
EvolutionaryTrace	Q858G8
Proteomes	UP000001770
GO	GO:0019028

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0019028	viral capsid	PMID:23840063	ECO:0000250		UniProtKB:P49861	C		Figure S6 in the supporting information document shows the structural homologs of gp7. Gp7 is a protein subunit of the capsid of epsilon15. The overall structure of gp7 is similar to the canonical bacteriophage coat proteins in tailed dsDNA bacteriophage. When the gp7 model is compared to the gp5 of HK97, the two structures are remarkably very similar. The two structures are nearly identical for about the first 145 amino acids. However, a domain swap in gp7 creates a 55% structural similarity according to CLICK. The two structures have a topology score of 1.0 according to CLICK. Therefore, the high structural similarity between HK97 gp5 and e15 gp7, provides further validation of the gp7 model. The evolutionary lineage of the e15 phage shows a highly conserved structural folding as supported by gp5 of HK97.	complete CACAO 12605
	GO:0019028	viral capsid	Pubmed uniprot:Pubmed uniprot	ECO:0000250		UniProtKB:A0A0L5RKM7	C		The sequence was run on blast and the results showed a lot of similarity between the major capsid protein in epsilon15 and Salmonella enterica. There was an e-value of 0.0 and a percent identity of 100%, as well as a query cover of 100. This proves that there is a capsid protein in epsilon15.	complete CACAO 12608
	GO:0019028	viral capsid	PMID:23840063	ECO:0000250		UniProtKB:Q9WR38	C		X-ray crystallographic modeling tools were used to refine gp10 models. The gp10 refined model depicts an eight-stranded jellyroll fold. Using DALI, structural similarity was determined among various viruses with the same jellyroll fold. Figure S8 shows the structural homologs of the gp10 models. Gp10 is a protein subunit of the capsid of bacteriophage, epsilon15. Part A of figure S8 shows gp10's interaction with the exposed surface and the capsid surface. According to DALI, the top score of structural similarity to the gp10 of epsilon15 was given to the projecting jellyroll domain of the virus VP2 (PDB ID: 2DF7, Z-score = 6.3). Despite a difference in its length and sequence, gp10 and 2DF7 domain structure share a similar folding pattern. The topology of these two structures are identical. The high structural match between these two structures further validates the gp10 model.	complete CACAO 12607
Colocalizes with	GO:0019028	viral capsid	GO_REF:0000100	ECO:0000247		UniProtKB:A0A0M1T664	C		Blast P shows a 100% Query Coverage. Matches with Salmonella phage epsilon15(Q858G8) with Klebsiella pneumoniae phage (A0A0M1T664) with an E Value of 0.0. This proves that there is a capsid protein	complete CACAO 12610
Colocalizes with	GO:0019028	viral capsid	GO_REF:0000100	ECO:0000247		UniProtKB:A0A1B6W0F5 UniProtKB:Q858G8	C		The Blastp shows when Q858G8 is blasted has a 99% Query Coverage and an e value of 6 e-96 with A0A1B6W0F5 UniProt ID which Identifies as Major Capsid Protein of eikenella sp phage.	complete CACAO 12669
	GO:0019028	viral capsid	GO:0000100	ECO:0000250		UniProtKB:H2D0E5	C		Comparison of the epsilon15 sequence to the sequence database using blatp showed that a region in epsilon15 and the major capsid protein in salmonella phage SPN1S have very close similarity. There was a percent Identity of a 100%, an Evalue of 0.0, and a query value of a 100. This shows that epsilon 15 has a major capsid protein.	complete CACAO 12670
	GO:0019028	viral capsid	0000100:0000100	ECO:0000250		UniProtKB:M1F234	C		Comparison of the epsilon15 sequence to the sequence database using blatp showed that a region in epsilon15 and the major capsid protein in salmonella phage SPN9TCW have very close similarity. There was a percent Identity of a 100%, an Evalue of 0.0, and a query value of a 100. This shows that epsilon15 has a major capsid protein.	complete CACAO 12671
part_of	GO:0019028	viral capsid	PMID:23840063	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
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