BOVIN:K6PF

Species (Taxon ID)	Bos taurus (Bovine). (9913)
Gene Name(s)	PFKM
Protein Name(s)	6-phosphofructokinase, muscle type Phosphofructo-1-kinase isozyme A PFK-A Phosphofructokinase-M Phosphofructokinase 1 Phosphohexokinase
External Links
UniProt	Q0IIG5
EMBL	BC122655
RefSeq	NP_001068736.1
UniGene	Bt.61411
ProteinModelPortal	Q0IIG5
STRING	9913.ENSBTAP00000000358
PaxDb	Q0IIG5
PRIDE	Q0IIG5
Ensembl	ENSBTAT00000000359
GeneID	506544
KEGG	bta:506544
CTD	5213
eggNOG	COG0205
GeneTree	ENSGT00390000013209
HOGENOM	HOG000200154
HOVERGEN	HBG000976
InParanoid	Q0IIG5
KO	K00850
OMA	VYHMASK
OrthoDB	EOG7ZSHV5
TreeFam	TF300411
UniPathway	UPA00109
NextBio	20867650
GO	GO:0005945 GO:0016324 GO:0003872 GO:0005524 GO:0070061 GO:0046872 GO:0046835 GO:0006002 GO:0042593 GO:0006096 GO:0046716 GO:0032024 GO:0051259
HAMAP	MF_00339
InterPro	IPR009161 IPR022953 IPR015912 IPR000023
Pfam	PF00365
PIRSF	PIRSF000533
PRINTS	PR00476
SUPFAM	SSF53784
TIGRFAMs	TIGR02478
PROSITE	PS00433

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0005516	calmodulin binding	PMID:6223841^[1]	ECO:0000314			F		complete
enables	GO:0003872	6-phosphofructokinase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00511	F	Seeded From UniProt	complete
part_of	GO:0097228	sperm principal piece	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97548 PANTHER:PTN002672135	C	Seeded From UniProt	complete
enables	GO:0070095	fructose-6-phosphate binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000344216 PomBase:SPBC16H5.02 RGD:3311 RGD:61893 RGD:68419 UniProtKB:P17858	F	Seeded From UniProt	complete
involved_in	GO:0061621	canonical glycolysis	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97548 PANTHER:PTN000344216	P	Seeded From UniProt	complete
enables	GO:0048029	monosaccharide binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000344216 RGD:3311	F	Seeded From UniProt	complete
involved_in	GO:0046716	muscle cell cellular homeostasis	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002672135 UniProtKB:P08237	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97548 PANTHER:PTN002672135	F	Seeded From UniProt	complete
involved_in	GO:0030388	fructose 1,6-bisphosphate metabolic process	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000344216 PomBase:SPBC16H5.02 RGD:3311 RGD:61893 RGD:68419 UniProtKB:P17858	P	Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002672135 UniProtKB:P08237	C	Seeded From UniProt	complete
enables	GO:0016208	AMP binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000344216 RGD:68419	F	Seeded From UniProt	complete
involved_in	GO:0006007	glucose catabolic process	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10699 PANTHER:PTN000344216 dictyBase:DDB_G0274111	P	Seeded From UniProt	complete
involved_in	GO:0006002	fructose 6-phosphate metabolic process	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97547 PANTHER:PTN000344216 PomBase:SPBC16H5.02 RGD:3311 RGD:61893 RGD:68419 UniProtKB:P08237 UniProtKB:P17858 dictyBase:DDB_G0274111	P	Seeded From UniProt	complete
part_of	GO:0005945	6-phosphofructokinase complex	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10699 PANTHER:PTN000344216 PomBase:SPBC16H5.02 SGD:S000003472 SGD:S000004818 UniProtKB:P08237 UniProtKB:P17858 dictyBase:DDB_G0274111	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002672135 UniProtKB:P08237	C	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10699 PANTHER:PTN000344216 PomBase:SPBC16H5.02 RGD:3311 RGD:61893 RGD:68419 UniProtKB:P08237 UniProtKB:P17858	F	Seeded From UniProt	complete
enables	GO:0003872	6-phosphofructokinase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10699 FB:FBgn0003071 MGI:MGI:97548 PANTHER:PTN000344216 PomBase:SPBC16H5.02 RGD:61893 RGD:68419 UniProtKB:P08237 UniProtKB:Q01813 dictyBase:DDB_G0274111	F	Seeded From UniProt	complete
enables	GO:0003872	6-phosphofructokinase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10699 FB:FBgn0003071 MGI:MGI:97547 MGI:MGI:97548 PANTHER:PTN000344216 PomBase:SPBC16H5.02 RGD:3311 RGD:61893 RGD:68419 SGD:S000003472 SGD:S000004818 UniProtKB:P08237 UniProtKB:P17858 UniProtKB:Q01813 dictyBase:DDB_G0274111	F	Seeded From UniProt	complete
enables	GO:0003872	6-phosphofructokinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000023 InterPro:IPR009161 InterPro:IPR015912 InterPro:IPR022953 InterPro:IPR035966	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR009161	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR009161	C	Seeded From UniProt	complete
involved_in	GO:0006002	fructose 6-phosphate metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR022953	P	Seeded From UniProt	complete
involved_in	GO:0006096	glycolytic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000023 InterPro:IPR009161 InterPro:IPR015912 InterPro:IPR022953 InterPro:IPR035966	P	Seeded From UniProt	complete
enables	GO:0003872	6-phosphofructokinase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.1.11	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000166259	C	Seeded From UniProt	complete
involved_in	GO:0006096	glycolytic process	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000166259	P	Seeded From UniProt	complete
enables	GO:0003872	6-phosphofructokinase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000166259	F	Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0021	F	Seeded From UniProt	complete
involved_in	GO:0006096	glycolytic process	GO_REF:0000037 GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0324 UniPathway:UPA00109	P	Seeded From UniProt	complete
involved_in	GO:0008152	metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0021	P	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Mayr, GW & Heilmeyer, LM Jr (1983) Phosphofructokinase is a calmodulin binding protein. FEBS Lett. 159 51-7 PubMed GONUTS page
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:6223841-1] Mayr, GW & Heilmeyer, LM Jr (1983) Phosphofructokinase is a calmodulin binding protein. FEBS Lett. 159 51-7 PubMed GONUTS page

[PMID:21873635-2] 2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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BOVIN:K6PF

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