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BOVIN:CRYAA

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Species (Taxon ID) Bos taurus (Bovine). (9913)
Gene Name(s) CRYAA (synonyms: CRYA1)
Protein Name(s) Alpha-crystallin A chain

Alpha-crystallin A(1-172) Alpha-crystallin A(1-168)

External Links
UniProt P02470
EMBL M26142
PIR A29656
RefSeq NP_776714.1
UniGene Bt.397
PDB 3L1E
3L1F
PDBsum 3L1E
3L1F
ProteinModelPortal P02470
DIP DIP-58566N
STRING 9913.ENSBTAP00000004073
UniCarbKB P02470
PRIDE P02470
Ensembl ENSBTAT00000004073
GeneID 281718
KEGG bta:281718
CTD 1409
eggNOG NOG278874
GeneTree ENSGT00760000119238
HOGENOM HOG000233954
HOVERGEN HBG054766
InParanoid P02470
KO K09541
OMA GPKVQSG
OrthoDB EOG7WHHBK
TreeFam TF105049
EvolutionaryTrace P02470
NextBio 20805639
Proteomes UP000009136
GO GO:0005737
GO:0005634
GO:0046872
GO:0005212
GO:0051082
GO:0007015
GO:0060561
GO:0048596
GO:0070309
GO:0007017
GO:0007005
GO:0043154
GO:0030307
GO:0001934
GO:0042542
GO:0001666
GO:0070141
GO:0007021
Gene3D 2.60.40.790
InterPro IPR002068
IPR001436
IPR012274
IPR003090
IPR008978
PANTHER PTHR11527:SF36
Pfam PF00525
PF00011
PIRSF PIRSF036514
PRINTS PR00299
SUPFAM SSF49764
PROSITE PS01031

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0051082

unfolded protein binding

PMID:7487869[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

NOT|involved_in

GO:0042026

protein refolding

PMID:7487869[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:7487869[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P02489

C

Seeded From UniProt

complete

involved_in

GO:0070309

lens fiber cell morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0070141

response to UV-A

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0060561

apoptotic process involved in morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0048596

embryonic camera-type eye morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0043154

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0043066

negative regulation of apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0043010

camera-type eye development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0042542

response to hydrogen peroxide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0030307

positive regulation of cell growth

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0010629

negative regulation of gene expression

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0007021

tubulin complex assembly

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0007017

microtubule-based process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0007015

actin filament organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0007005

mitochondrion organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0006915

apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

C

Seeded From UniProt

complete

involved_in

GO:0002089

lens morphogenesis in camera-type eye

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0002088

lens development in camera-type eye

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0001934

positive regulation of protein phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

involved_in

GO:0001666

response to hypoxia

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P24622
ensembl:ENSMUSP00000019192

P

Seeded From UniProt

complete

enables

GO:0005212

structural constituent of eye lens

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003090
InterPro:IPR012274

F

Seeded From UniProt

complete

enables

GO:0005212

structural constituent of eye lens

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0273

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Das, KP & Surewicz, WK (1995) On the substrate specificity of alpha-crystallin as a molecular chaperone. Biochem. J. 311 ( Pt 2) 367-70 PubMed GONUTS page