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ARATH:XPF

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) UVH1 (synonyms: RAD1)
Protein Name(s) DNA repair endonuclease UVH1

DNA excision repair protein XP-F homolog Ultraviolet hypersensitive 1 AtRAD1

External Links
UniProt Q9LKI5
EMBL AF089003
AF160500
AF277377
AB010072
CP002688
AY140076
AF191494
RefSeq NP_198931.1
UniGene At.6598
At.71026
ProteinModelPortal Q9LKI5
SMR Q9LKI5
STRING 3702.AT5G41150.1
PaxDb Q9LKI5
EnsemblPlants AT5G41150.1
GeneID 834117
Gramene AT5G41150.1
KEGG ath:AT5G41150
Araport AT5G41150
TAIR locus:2163011
eggNOG KOG0442
COG1948
HOGENOM HOG000202204
InParanoid Q9LKI5
KO K10848
OMA RNVRVYF
OrthoDB EOG093601RF
PhylomeDB Q9LKI5
Reactome [www.reactome.org/content/detail/R-ATH-5696395 R-ATH-5696395]
[www.reactome.org/content/detail/R-ATH-5696400 R-ATH-5696400]
[www.reactome.org/content/detail/R-ATH-6782135 R-ATH-6782135]
PRO PR:Q9LKI5
Proteomes UP000006548
ExpressionAtlas Q9LKI5
Genevisible Q9LKI5
GO GO:0000110
GO:0003684
GO:0003697
GO:0000014
GO:0006281
GO:0000724
GO:0006289
GO:1901255
GO:0006296
GO:0000712
GO:0006979
GO:0009314
InterPro IPR006166
IPR011335
IPR010994
Pfam PF02732
SMART SM00891
SUPFAM SSF47781
SSF52980

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0000720

pyrimidine dimer repair by nucleotide-excision repair

PMID:10758502[1]

ECO:0000315

P

Figure 2D shows the recovery of the repair of (6-4) photoproduct in uvh1 plants transformed with UVH1/AtRAD1. Recovery is seen in both WT and transformed uvh1.

Organism: Arabidopsis thaliana

complete
CACAO 12971

GO:0006289

nucleotide-excision repair

PMID:10758502[1]

ECO:0000247

UniProtKB:Q92889


P

Figure 4 shows sequence alignment to XPF human (and other homologous DNA proteins for nucleotide excision repair) to UVH1.

Organism: Arabidopsis thaliana

complete
CACAO 12992

involved_in

GO:0009314

response to radiation

PMID:15133154[2]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006979

response to oxidative stress

PMID:11826311[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006289

nucleotide-excision repair

PMID:11027708[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

PMID:15053760[5]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

PMID:12393748[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000014

single-stranded DNA endodeoxyribonuclease activity

PMID:11027708[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:1901255

nucleotide-excision repair involved in interstrand cross-link repair

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000015911
PomBase:SPCC970.01

P

Seeded From UniProt

complete

involved_in

GO:0006296

nucleotide-excision repair, DNA incision, 5'-to lesion

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000015911
SGD:S000005943
UniProtKB:Q92889

P

Seeded From UniProt

complete

enables

GO:0003697

single-stranded DNA binding

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000015911
SGD:S000005943
UniProtKB:Q92889

F

Seeded From UniProt

complete

enables

GO:0003684

damaged DNA binding

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000015911
UniProtKB:Q92889

F

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000015911
PomBase:SPCC970.01
UniProtKB:Q92889
UniProtKB:Q9LKI5
dictyBase:DDB_G0284419

P

Seeded From UniProt

complete

involved_in

GO:0000712

resolution of meiotic recombination intermediates

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0002707
PANTHER:PTN000015911
WB:WBGene00008140

P

Seeded From UniProt

complete

part_of

GO:0000110

nucleotide-excision repair factor 1 complex

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000015911
PomBase:SPCC970.01
SGD:S000005943
UniProtKB:Q92889

C

Seeded From UniProt

complete

enables

GO:0000014

single-stranded DNA endodeoxyribonuclease activity

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000015911
SGD:S000005943
UniProtKB:Q9LKI5

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006166

F

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006166

F

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0255

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

complete

involved_in

GO:0006310

DNA recombination

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0233

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0228
UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Liu, Z et al. (2000) Repair of UV damage in plants by nucleotide excision repair: Arabidopsis UVH1 DNA repair gene is a homolog of Saccharomyces cerevisiae Rad1. Plant J. 21 519-28 PubMed GONUTS page
  2. Kovalchuk, I et al. (2004) Molecular aspects of plant adaptation to life in the Chernobyl zone. Plant Physiol. 135 357-63 PubMed GONUTS page
  3. Li, A et al. (2002) Repair of damaged DNA by Arabidopsis cell extract. Plant Cell 14 263-73 PubMed GONUTS page
  4. 4.0 4.1 Fidantsef, AL et al. (2000) The Arabidopsis UVH1 gene is a homolog of the yeast repair endonuclease RAD1. Plant Physiol. 124 579-86 PubMed GONUTS page
  5. Filkowski, J et al. (2004) Genome stability of vtc1, tt4, and tt5 Arabidopsis thaliana mutants impaired in protection against oxidative stress. Plant J. 38 60-9 PubMed GONUTS page
  6. Dubest, S et al. (2002) Role of the AtRad1p endonuclease in homologous recombination in plants. EMBO Rep. 3 1049-54 PubMed GONUTS page
  7. 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page