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ARATH:RDR1

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) RDR1 (synonyms: RDRP1)
Protein Name(s) RNA-dependent RNA polymerase 1

AtRDRP1 RNA-directed RNA polymerase 1

External Links
UniProt Q9LQV2
EMBL AY148431
AC006917
CP002684
AK228731
AJ011977
RefSeq NP_172932.1
UniGene At.27823
At.70434
ProteinModelPortal Q9LQV2
SMR Q9LQV2
STRING 3702.AT1G14790.1-P
PaxDb Q9LQV2
PRIDE Q9LQV2
EnsemblPlants AT1G14790.1
GeneID 838044
KEGG ath:AT1G14790
TAIR AT1G14790
eggNOG NOG307726
HOGENOM HOG000239464
InParanoid Q9LQV2
KO K11699
OMA EVAMKCN
PhylomeDB Q9LQV2
BioCyc ARA:AT1G14790-MONOMER
Proteomes UP000006548
Genevestigator Q9LQV2
GO GO:0003723
GO:0003968
GO:0006952
GO:0031047
GO:0060148
GO:0009751
GO:0009615
GO:0010025
InterPro IPR007855
PANTHER PTHR23079
Pfam PF05183

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0030422

production of siRNA involved in RNA interference

PMID:20190077[1]

ECO:0000315

P

Notes: Fig. 8 shows significant differences in TuMV-GFP–derived siRNA accumulation among the mutants; accumulation of siRNAs derived from the cylindrical inclusion (CI) or from the 5′ UTR of TuMV was significantly reduced in each single, double, and triple mutants with the rdr1-1 allele. This suggests that RDR1 is a major contributor to biogenesis of TuMV-derived siRNAs.

complete
CACAO 8265

involved_in

GO:0030422

production of siRNA involved in RNA interference

PMID:20190077[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0060148

positive regulation of posttranscriptional gene silencing

PMID:17586651[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010025

wax biosynthetic process

PMID:22689894[3]

ECO:0000316

genetic interaction evidence used in manual assertion

AGI_LocusCode:AT3G60500

P

Seeded From UniProt

complete

involved_in

GO:0009751

response to salicylic acid

PMID:15024409[4]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009615

response to virus

PMID:12650452[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0070919

production of siRNA involved in chromatin silencing by small RNA

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000554964
PomBase:SPAC6F12.09
TAIR:locus:2136068

P

Seeded From UniProt

complete

part_of

GO:0031380

nuclear RNA-directed RNA polymerase complex

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000554964
PomBase:SPAC6F12.09

C

Seeded From UniProt

complete

involved_in

GO:0030422

production of siRNA involved in RNA interference

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000554964
TAIR:locus:2006822
TAIR:locus:2136068
WB:WBGene00004508
dictyBase:DDB_G0280963

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000554964
PomBase:SPAC6F12.09
TAIR:locus:2114633
TAIR:locus:2136068
WB:WBGene00001214
WB:WBGene00004508

C

Seeded From UniProt

complete

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000554964
PomBase:SPAC6F12.09
WB:WBGene00004508

F

Seeded From UniProt

complete

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

complete

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

complete

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

complete

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR035979

F

Seeded From UniProt

complete

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007855

F

Seeded From UniProt

complete

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.7.48

F

Seeded From UniProt

complete

involved_in

GO:0031047

gene silencing by RNA

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0943

P

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

enables

GO:0016779

nucleotidyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0548

F

Seeded From UniProt

complete

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0696

F

Seeded From UniProt

complete

involved_in

GO:0006952

defense response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0611

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 Garcia-Ruiz, H et al. (2010) Arabidopsis RNA-dependent RNA polymerases and dicer-like proteins in antiviral defense and small interfering RNA biogenesis during Turnip Mosaic Virus infection. Plant Cell 22 481-96 PubMed GONUTS page
  2. ↑ Diaz-Pendon, JA et al. (2007) Suppression of antiviral silencing by cucumber mosaic virus 2b protein in Arabidopsis is associated with drastically reduced accumulation of three classes of viral small interfering RNAs. Plant Cell 19 2053-63 PubMed GONUTS page
  3. ↑ Lam, P et al. (2012) RDR1 and SGS3, components of RNA-mediated gene silencing, are required for the regulation of cuticular wax biosynthesis in developing inflorescence stems of Arabidopsis. Plant Physiol. 159 1385-95 PubMed GONUTS page
  4. ↑ Xie, Z et al. (2004) Genetic and functional diversification of small RNA pathways in plants. PLoS Biol. 2 E104 PubMed GONUTS page
  5. ↑ Yu, D et al. (2003) Analysis of the involvement of an inducible Arabidopsis RNA-dependent RNA polymerase in antiviral defense. Mol. Plant Microbe Interact. 16 206-16 PubMed GONUTS page
  6. ↑ 6.0 6.1 6.2 6.3 6.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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