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ARATH:RAD51

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) RAD51
Protein Name(s) DNA repair protein RAD51 homolog 1

Rad51-like protein 1 AtRAD51

External Links
UniProt P94102
EMBL U43652
AJ001100
U43528
AF296834
CP002688
RefSeq NP_568402.1
UniGene At.110
ProteinModelPortal P94102
SMR P94102
BioGrid 17483
DIP DIP-31780N
IntAct P94102
STRING 3702.AT5G20850.1-P
EnsemblPlants AT5G20850.1
GeneID 832208
KEGG ath:AT5G20850
GeneFarm 4757
TAIR AT5G20850
eggNOG COG0468
HOGENOM HOG000227426
InParanoid P94102
KO K04482
OMA CQLPIDQ
PhylomeDB P94102
Reactome REACT_249494
REACT_251609
PRO PR:P94102
Proteomes UP000006548
Genevestigator P94102
GO GO:0005694
GO:0005634
GO:0005524
GO:0003684
GO:0008094
GO:0006259
GO:0006302
GO:0045003
GO:0006355
GO:0010332
GO:0009314
Gene3D 3.40.50.300
InterPro IPR003593
IPR011941
IPR013632
IPR016467
IPR010995
IPR003583
IPR027417
IPR020588
IPR020587
Pfam PF08423
PIRSF PIRSF005856
SMART SM00382
SM00278
SUPFAM SSF47794
SSF52540
TIGRFAMs TIGR02239
PROSITE PS50162
PS50163

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045003

double-strand break repair via synthesis-dependent strand annealing

PMID:22860689[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010332

response to gamma radiation

PMID:20227352[2]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010332

response to gamma radiation

PMID:17227544[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009314

response to radiation

PMID:9520262[4]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:21149701[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006302

double-strand break repair

PMID:17921313[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006259

DNA metabolic process

PMID:20227352[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005694

chromosome

PMID:22381039[7]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:16442857[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0070192

chromosome organization involved in meiotic cell cycle

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97890
PANTHER:PTN000534635

P

Seeded From UniProt

complete

involved_in

GO:0042148

strand invasion

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001415033
PomBase:SPAC644.14c
PomBase:SPAC8E11.03c
SGD:S000000897

P

Seeded From UniProt

complete

enables

GO:0008094

DNA-dependent ATPase activity

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001415033
PomBase:SPAC8E11.03c
SGD:S000000897
UniProtKB:Q8IIS8
WB:WBGene00004297

F

Seeded From UniProt

complete

involved_in

GO:0007131

reciprocal meiotic recombination

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000534635
SGD:S000000897

P

Seeded From UniProt

complete

involved_in

GO:0006312

mitotic recombination

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001415033
PomBase:SPAC644.14c
UniProtKB:C8VSQ3

P

Seeded From UniProt

complete

enables

GO:0003697

single-stranded DNA binding

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97890
PANTHER:PTN001415033
PomBase:SPAC644.14c
PomBase:SPAC8E11.03c
SGD:S000000897
SGD:S000000981
UniProtKB:A0A1D8PFE4
UniProtKB:Q06609

F

Seeded From UniProt

complete

enables

GO:0003690

double-stranded DNA binding

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001415033
PomBase:SPAC644.14c
PomBase:SPAC8E11.03c
SGD:S000000981
UniProtKB:A0A1D8PFE4
UniProtKB:Q06609
WB:WBGene00004297

F

Seeded From UniProt

complete

part_of

GO:0000794

condensed nuclear chromosome

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97890
PANTHER:PTN000534635
SGD:S000000897
WB:WBGene00004297

C

Seeded From UniProt

complete

involved_in

GO:0000730

DNA recombinase assembly

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001415033
PomBase:SPAC20H4.07
SGD:S000002411
UniProtKB:Q06609

P

Seeded From UniProt

complete

enables

GO:0000150

recombinase activity

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001415033
PomBase:SPAC644.14c
PomBase:SPAC8E11.03c
SGD:S000000897
SGD:S000000981
UniProtKB:Q8IIS8
WB:WBGene00004297

F

Seeded From UniProt

complete

enables

GO:0000150

recombinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011941

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010995

F

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011941

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020587
InterPro:IPR020588
InterPro:IPR033925

F

Seeded From UniProt

complete

enables

GO:0003690

double-stranded DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011941

F

Seeded From UniProt

complete

enables

GO:0003697

single-stranded DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011941

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020587
InterPro:IPR020588

F

Seeded From UniProt

complete

involved_in

GO:0006259

DNA metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020587

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020588

P

Seeded From UniProt

complete

enables

GO:0008094

DNA-dependent ATPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011941
InterPro:IPR020587
InterPro:IPR020588

F

Seeded From UniProt

complete

involved_in

GO:1990426

mitotic recombination-dependent replication fork processing

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011941

P

Seeded From UniProt

complete

involved_in

GO:0006259

DNA metabolic process

PMID:9520262[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0006310

DNA recombination

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0233

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Roth, N et al. (2012) The requirement for recombination factors differs considerably between different pathways of homologous double-strand break repair in somatic plant cells. Plant J. 72 781-90 PubMed GONUTS page
  2. 2.0 2.1 Siaud, N et al. (2010) The SOS screen in Arabidopsis: a search for functions involved in DNA metabolism. DNA Repair (Amst.) 9 567-78 PubMed GONUTS page
  3. Osakabe, K et al. (2006) Isolation and characterization of the RAD54 gene from Arabidopsis thaliana. Plant J. 48 827-42 PubMed GONUTS page
  4. 4.0 4.1 Doutriaux, MP et al. (1998) Isolation and characterisation of the RAD51 and DMC1 homologs from Arabidopsis thaliana. Mol. Gen. Genet. 257 283-91 PubMed GONUTS page
  5. Wang, S et al. (2010) Arabidopsis BRCA2 and RAD51 proteins are specifically involved in defense gene transcription during plant immune responses. Proc. Natl. Acad. Sci. U.S.A. 107 22716-21 PubMed GONUTS page
  6. Markmann-Mulisch, U et al. (2007) Differential requirements for RAD51 in Physcomitrella patens and Arabidopsis thaliana development and DNA damage repair. Plant Cell 19 3080-9 PubMed GONUTS page
  7. Yuan, L et al. (2012) The Arabidopsis SYN3 cohesin protein is important for early meiotic events. Plant J. 71 147-60 PubMed GONUTS page
  8. Domenichini, S et al. (2006) Atmnd1-delta1 is sensitive to gamma-irradiation and defective in meiotic DNA repair. DNA Repair (Amst.) 5 455-64 PubMed GONUTS page
  9. 9.0 9.1 9.2 9.3 9.4 9.5 9.6 9.7 9.8 9.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page