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ARATH:AUX1

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Species (Taxon ID) Arabidopsis thaliana (Mouse-ear cress). (3702)
Gene Name(s) AUX1 (synonyms: AUX, PIR1, WAV5)
Protein Name(s) Auxin transporter protein 1

Auxin influx carrier protein 1 Polar auxin transport inhibitor-resistant protein 1

External Links
UniProt Q96247
EMBL X98772
AC003028
CP002685
AY054488
AY093300
AY087092
PIR T01244
RefSeq NP_565882.1
UniGene At.24295
ProteinModelPortal Q96247
STRING 3702.AT2G38120.1-P
TCDB 2.A.18.1.1
PaxDb Q96247
PRIDE Q96247
EnsemblPlants AT2G38120.1
GeneID 818390
KEGG ath:AT2G38120
TAIR AT2G38120
eggNOG NOG319329
HOGENOM HOG000238482
InParanoid Q96247
KO K13946
OMA KNAWRDA
PhylomeDB Q96247
Proteomes UP000006548
Genevestigator Q96247
GO GO:0009986
GO:0005768
GO:0005794
GO:0016021
GO:0005886
GO:0015171
GO:0010011
GO:0010328
GO:0015293
GO:0003333
GO:0060919
GO:0009926
GO:0009734
GO:0001736
GO:0010311
GO:0009958
GO:0009624
GO:0048829
GO:0048765
InterPro IPR013057
Pfam PF01490

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0048767

root hair elongation

PMID:10036773[1]

ECO:0000314

P

figures 4 and 5 show that AUX1 causes root hair development over time through microscopy.

complete
CACAO 4341

GO:0009958

positive gravitropism

PMID:10205161[2]

ECO:0000269

P

figure 3 shows that AUX1 restores gravitropic root growth.

complete
CACAO 4348

involved_in

GO:0048829

root cap development

PMID:19952011[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048765

root hair cell differentiation

PMID:17084699[4]

ECO:0000316

genetic interaction evidence used in manual assertion

AGI_LocusCode:AT1G13980
AGI_LocusCode:AT5G03280

P

Seeded From UniProt

complete

enables

GO:0015171

amino acid transmembrane transporter activity

PMID:9484486[5]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

enables

GO:0010328

auxin influx transmembrane transporter activity

PMID:16677815[6]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0010311

lateral root formation

PMID:18622388[7]

ECO:0000316

genetic interaction evidence used in manual assertion

AGI_LocusCode:AT1G77690

P

Seeded From UniProt

complete

involved_in

GO:0010311

lateral root formation

PMID:17215297[8]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0010011

auxin binding

PMID:18614710[9]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:11641271[10]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0009958

positive gravitropism

PMID:8688077[11]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009624

response to nematode

PMID:16478044[12]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:16690816[13]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:17114355[14]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005768

endosome

PMID:17114355[14]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0001736

establishment of planar polarity

PMID:17084699[4]

ECO:0000316

genetic interaction evidence used in manual assertion

AGI_LocusCode:AT1G13980
AGI_LocusCode:AT5G03280

P

Seeded From UniProt

complete

enables

GO:0015171

amino acid transmembrane transporter activity

PMID:21873635[15]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0035300
FB:FBgn0036007
MGI:MGI:1915010
PANTHER:PTN000535793
RGD:620702
RGD:621836
TAIR:locus:2016600
TAIR:locus:2154815
TAIR:locus:2172868
TAIR:locus:2184707
TAIR:locus:2201871
UniProtKB:Q8NBW4

F

Seeded From UniProt

complete

involved_in

GO:0003333

amino acid transmembrane transport

PMID:21873635[15]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0035300
FB:FBgn0036007
PANTHER:PTN000535793
SGD:S000003761
TAIR:locus:2184707
UniProtKB:Q8NBW4

P

Seeded From UniProt

complete

involved_in

GO:0060919

auxin influx

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0010328

P

Seeded From UniProt

complete

involved_in

GO:0009926

auxin polar transport

PMID:16839804[16]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006865

amino acid transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0029

P

Seeded From UniProt

complete

enables

GO:0015293

symporter activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0769

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0009734

auxin-activated signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0927

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Pitts, RJ et al. (1998) Auxin and ethylene promote root hair elongation in Arabidopsis. Plant J. 16 553-60 PubMed GONUTS page
  2. Marchant, A et al. (1999) AUX1 regulates root gravitropism in Arabidopsis by facilitating auxin uptake within root apical tissues. EMBO J. 18 2066-73 PubMed GONUTS page
  3. Ugartechea-Chirino, Y et al. (2010) The AUX1 LAX family of auxin influx carriers is required for the establishment of embryonic root cell organization in Arabidopsis thaliana. Ann. Bot. 105 277-89 PubMed GONUTS page
  4. 4.0 4.1 Fischer, U et al. (2006) Vectorial information for Arabidopsis planar polarity is mediated by combined AUX1, EIN2, and GNOM activity. Curr. Biol. 16 2143-9 PubMed GONUTS page
  5. Marchant, A & Bennett, MJ (1998) The Arabidopsis AUX1 gene: a model system to study mRNA processing in plants. Plant Mol. Biol. 36 463-71 PubMed GONUTS page
  6. Yang, Y et al. (2006) High-affinity auxin transport by the AUX1 influx carrier protein. Curr. Biol. 16 1123-7 PubMed GONUTS page
  7. Swarup, K et al. (2008) The auxin influx carrier LAX3 promotes lateral root emergence. Nat. Cell Biol. 10 946-54 PubMed GONUTS page
  8. De Smet, I et al. (2007) Auxin-dependent regulation of lateral root positioning in the basal meristem of Arabidopsis. Development 134 681-90 PubMed GONUTS page
  9. Carrier, DJ et al. (2008) The binding of auxin to the Arabidopsis auxin influx transporter AUX1. Plant Physiol. 148 529-35 PubMed GONUTS page
  10. Swarup, R et al. (2001) Localization of the auxin permease AUX1 suggests two functionally distinct hormone transport pathways operate in the Arabidopsis root apex. Genes Dev. 15 2648-53 PubMed GONUTS page
  11. Bennett, MJ et al. (1996) Arabidopsis AUX1 gene: a permease-like regulator of root gravitropism. Science 273 948-50 PubMed GONUTS page
  12. Hammes, UZ et al. (2005) Nematode-induced changes of transporter gene expression in Arabidopsis roots. Mol. Plant Microbe Interact. 18 1247-57 PubMed GONUTS page
  13. Dharmasiri, S et al. (2006) AXR4 is required for localization of the auxin influx facilitator AUX1. Science 312 1218-20 PubMed GONUTS page
  14. 14.0 14.1 Kleine-Vehn, J et al. (2006) Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1. Plant Cell 18 3171-81 PubMed GONUTS page
  15. 15.0 15.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  16. Kramer, EM & Bennett, MJ (2006) Auxin transport: a field in flux. Trends Plant Sci. 11 382-6 PubMed GONUTS page