PMID:11641271

Citation	Swarup, R, Friml, J, Marchant, A, Ljung, K, Sandberg, G, Palme, K and Bennett, M (2001) Localization of the auxin permease AUX1 suggests two functionally distinct hormone transport pathways operate in the Arabidopsis root apex. Genes Dev. 15:2648-53
Abstract	Auxins represent an important class of plant hormone that regulate plant development. Plants use specialized carrier proteins to transport the auxin indole-3-acetic acid (IAA) to target tissues. To date, efflux carrier-mediated polar auxin transport has been assumed to represent the sole mode of long distance IAA movement. Localization of the auxin permease AUX1 in the Arabidopsis root apex has revealed a novel phloem-based IAA transport pathway. AUX1, asymmetrically localized to the plasma membrane of root protophloem cells, is proposed to promote the acropetal, post-phloem movement of auxin to the root apex. MS analysis shows that IAA accumulation in aux1 mutant root apices is impaired, consistent with an AUX1 phloem unloading function. AUX1 localization to columella and lateral root cap tissues of the Arabidopsis root apex reveals that the auxin permease regulates a second IAA transport pathway. Expression studies using an auxin-regulated reporter suggest that AUX1 is necessary for root gravitropism by facilitating basipetal auxin transport to distal elongation zone tissues.
Links	PubMed PMC312818 Online version:10.1101/gad.210501
Keywords	Arabidopsis/metabolism; Arabidopsis Proteins; Biological Transport; Cells, Cultured/cytology; Epitopes; Indoleacetic Acids/metabolism; Membrane Proteins/metabolism; Membrane Transport Proteins; Plant Growth Regulators/metabolism; Plant Proteins/metabolism; Plant Roots/cytology; Plant Roots/metabolism; Plants, Genetically Modified; Promoter Regions, Genetic; Signal Transduction; Subcellular Fractions
edit table

Annotations

Gene product	Qualifier	GO ID	GO term name	Evidence Code	with/from	Aspect	Notes	Status
edit table

References

See Help:References for how to manage references in GONUTS.