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AQUAE:DNAG

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Species (Taxon ID) Aquifex aeolicus (strain VF5). (224324)
Gene Name(s) dnaG (ECO:0000255 with HAMAP-Rule:MF_00974)
Protein Name(s) DNA primase (ECO:0000255 with HAMAP-Rule:MF_00974)
External Links
UniProt O67465
EMBL AE000657
PIR G70429
RefSeq NP_214030.1
WP_010880968.1
PDB 2AU3
PDBsum 2AU3
ProteinModelPortal O67465
SMR O67465
STRING 224324.aq_1493
EnsemblBacteria AAC07430
GeneID 1192996
KEGG aae:aq_1493
PATRIC 20960100
eggNOG ENOG4105C9G
COG0358
HOGENOM HOG000014483
InParanoid O67465
KO K02316
OMA CPFHPDD
OrthoDB EOG6XDGTR
BioCyc AAEO224324:GJBH-1072-MONOMER
EvolutionaryTrace O67465
Proteomes UP000000798
GO GO:1990077
GO:0003677
GO:0003896
GO:0000287
GO:0008270
Gene3D 3.90.580.10
3.90.980.10
HAMAP MF_00974
InterPro IPR013264
IPR006295
IPR030846
IPR006171
IPR002694
Pfam PF13662
PF08275
PF01807
SMART SM00493
SM00400
TIGRFAMs TIGR01391
PROSITE PS50880

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003896

DNA primase activity

PMID:16285921[1]

ECO:0000314

F

In figure 1a, The conserved b-sheet surface of the ZBD contacts the RPD, associating via several salt bridges and polar interactions, but is angled away by 45º to form a narrow groove between the two domains.

complete
CACAO 11887

involved_in

GO:0006269

DNA replication, synthesis of RNA primer

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10239
PANTHER:PTN001250916

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10239
PANTHER:PTN001250916

C

Seeded From UniProt

complete

enables

GO:0003896

DNA primase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10239
PANTHER:PTN001250916

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002694
InterPro:IPR036977

F

Seeded From UniProt

complete

enables

GO:0003896

DNA primase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002694
InterPro:IPR006295
InterPro:IPR030846

F

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002694
InterPro:IPR036977

P

Seeded From UniProt

complete

involved_in

GO:0006269

DNA replication, synthesis of RNA primer

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006295
InterPro:IPR030846

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002694
InterPro:IPR030846
InterPro:IPR036977

F

Seeded From UniProt

complete

enables

GO:0003896

DNA primase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000113487

F

Seeded From UniProt

complete

involved_in

GO:0006269

DNA replication, synthesis of RNA primer

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000113487

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000113487

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0006269

DNA replication, synthesis of RNA primer

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0639

P

Seeded From UniProt

complete

enables

GO:0016779

nucleotidyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0548

F

Seeded From UniProt

complete

part_of

GO:1990077

primosome complex

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0639

C

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0235

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0003899

DNA-directed 5'-3' RNA polymerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0240

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Corn, JE et al. (2005) Crosstalk between primase subunits can act to regulate primer synthesis in trans. Mol. Cell 20 391-401 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page