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Danio rerio (zebrafish)

acvr1:ACVR1 activin A receptor, type I
acvr1 on ZFIN

GO terms

GO:0000166_!_nucleotide_binding (F) IEA with/from SP_KW:KW-0547 [1]
GO:0001889_!_liver_development (P) IMP with/from ZFIN:ZDB-GENO-980202-960 [2]
GO:0001944_!_vasculature_development (P) IMP with/from ZFIN:ZDB-GENO-980202-960 [3]
GO:0001947_!_heart_looping (P) IMP with/from ZFIN:ZDB-GENO-980202-960 [4]
GO:0004672_!_protein_kinase_activity (F) IEA with/from InterPro:IPR000719 [5]
GO:0004672_!_protein_kinase_activity (F) IEA with/from InterPro:IPR017441 [5]
GO:0004672_!_protein_kinase_activity (F) IEA with/from InterPro:IPR017442 [5]
GO:0004674_!_protein_serine/threonine_kinase_activity (F) IEA with/from SP_KW:KW-0723 [1]
GO:0004674_!_protein_serine/threonine_kinase_activity (F) IEA with/from InterPro:IPR008271 [5]
GO:0004675_!_transmembrane_receptor_protein_serine/threonine_kinase_activity (F) IEA with/from InterPro:IPR000472 [5]
GO:0004675_!_transmembrane_receptor_protein_serine/threonine_kinase_activity (F) IEA with/from InterPro:IPR003605 [5]
GO:0004872_!_receptor_activity (F) IEA with/from SP_KW:KW-0675 [1]
GO:0005024_!_transforming_growth_factor_beta_receptor_activity (F) IEA with/from InterPro:IPR000472 [5]
GO:0005524_!_ATP_binding (F) IEA with/from SP_KW:KW-0067 [1]
GO:0005524_!_ATP_binding (F) IEA with/from InterPro:IPR000719 [5]
GO:0005524_!_ATP_binding (F) IEA with/from InterPro:IPR003605 [5]
GO:0005524_!_ATP_binding (F) IEA with/from InterPro:IPR017441 [5]
GO:0005524_!_ATP_binding (F) IEA with/from InterPro:IPR017442 [5]
GO:0005524_!_ATP_binding (F) ISS with/from UniProtKB:Q04771 [6]
GO:0005737_!_cytoplasm (C) IDA [7]
GO:0005887_!_integral_to_plasma_membrane (C) ISS with/from UniProtKB:P37172 [6]
GO:0005938_!_cell_cortex (C) IDA [7]
GO:0006468_!_protein_amino_acid_phosphorylation (P) IEA with/from InterPro:IPR000719 [5]
GO:0006468_!_protein_amino_acid_phosphorylation (P) IEA with/from InterPro:IPR003605 [5]
GO:0006468_!_protein_amino_acid_phosphorylation (P) IEA with/from InterPro:IPR008271 [5]
GO:0006468_!_protein_amino_acid_phosphorylation (P) IEA with/from InterPro:IPR017441 [5]
GO:0006468_!_protein_amino_acid_phosphorylation (P) IEA with/from InterPro:IPR017442 [5]
GO:0006468_!_protein_amino_acid_phosphorylation (P) ISS with/from UniProtKB:Q04771 [6]
GO:0007368_!_determination_of_left/right_symmetry (P) IMP with/from ZFIN:ZDB-GENO-061204-4 [8]
GO:0007420_!_brain_development (P) IMP [9]
GO:0009952_!_anterior/posterior_pattern_formation (P) IMP with/from ZFIN:ZDB-GENO-980202-960 [10]
GO:0009953_!_dorsal/ventral_pattern_formation (P) IGI with/from ZFIN:ZDB-GENE-980526-527 [11]
GO:0009953_!_dorsal/ventral_pattern_formation (P) IMP [11]
GO:0009953_!_dorsal/ventral_pattern_formation (P) IMP with/from ZFIN:ZDB-GENO-980202-960 [3]
GO:0009953_!_dorsal/ventral_pattern_formation (P) IMP with/from ZFIN:ZDB-GENO-980202-960 [12]
GO:0009953_!_dorsal/ventral_pattern_formation (P) IGI with/from ZFIN:ZDB-GENE-980526-373 [13]
GO:0009953_!_dorsal/ventral_pattern_formation (P) IMP [14]
GO:0016020_!_membrane (C) IEA with/from InterPro:IPR000472 [5]
GO:0016020_!_membrane (C) IEA with/from InterPro:IPR003605 [5]
GO:0016301_!_kinase_activity (F) IEA with/from SP_KW:KW-0418 [1]
GO:0016740_!_transferase_activity (F) IEA with/from SP_KW:KW-0808 [1]
GO:0021556_!_central_nervous_system_formation (P) IMP [11]
GO:0030509_!_BMP_signaling_pathway (P) IGI with/from ZFIN:ZDB-GENE-000208-25 [3]
GO:0030509_!_BMP_signaling_pathway (P) IGI with/from ZFIN:ZDB-GENE-980526-474 [3]
GO:0030510_!_regulation_of_BMP_signaling_pathway (P) IGI with/from ZFIN:ZDB-GENE-980526-373 [13]
GO:0030510_!_regulation_of_BMP_signaling_pathway (P) IMP with/from ZFIN:ZDB-GENO-980202-960 [9]
GO:0035050_!_embryonic_heart_tube_development (P) IMP with/from ZFIN:ZDB-GENO-080731-4 [15]
GO:0035050_!_embryonic_heart_tube_development (P) IMP with/from ZFIN:ZDB-GENO-061204-4 [8]
GO:0035124_!_embryonic_caudal_fin_morphogenesis (P) IMP with/from ZFIN:ZDB-GENO-980202-960 [3]
GO:0035162_!_embryonic_hemopoiesis (P) IMP with/from ZFIN:ZDB-GENO-060403-1 [16]
GO:0042475_!_odontogenesis_of_dentine-containing_tooth (P) IMP [17]
GO:0042476_!_odontogenesis (P) IEP [18]
GO:0046588_!_negative_regulation_of_calcium-dependent_cell-cell_adhesion (P) IDA [19]
GO:0046588_!_negative_regulation_of_calcium-dependent_cell-cell_adhesion (P) IMP with/from ZFIN:ZDB-MRPHLNO-060920-2 [19]
GO:0048264_!_determination_of_ventral_identity (P) IMP [11]
GO:0048264_!_determination_of_ventral_identity (P) IMP with/from ZFIN:ZDB-GENO-980202-960 [3]
GO:0048264_!_determination_of_ventral_identity (P) IDA [20]
GO:0048264_!_determination_of_ventral_identity (P) IMP [20]
GO:0048264_!_determination_of_ventral_identity (P) IMP with/from ZFIN:ZDB-GENO-980202-960 [20]
GO:0048264_!_determination_of_ventral_identity (P) IMP with/from ZFIN:ZDB-MRPHLNO-060920-1 ZFIN:ZDB-MRPHLNO-060920-2 [20]
GO:0048264_!_determination_of_ventral_identity (P) IMP [13]
GO:0048264_!_determination_of_ventral_identity (P) IMP [16]
GO:0048264_!_determination_of_ventral_identity (P) IMP [21]
GO:0048332_!_mesoderm_morphogenesis (P) IMP [11]
GO:0051216_!_cartilage_development (P) IMP [9]
GO:0060030_!_dorsal_convergence (P) IMP with/from ZFIN:ZDB-MRPHLNO-060920-2 [19]

The contents of this box are automatically generated. You can help by adding information to the "Notes"



See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 ZFIN:ZDB-PUB-020723-1 ZFIN:ZDB-PUB-020723-1
  2. Shin, D et al. (2007) Bmp and Fgf signaling are essential for liver specification in zebrafish. Development 134 2041-50 PubMed GONUTS page ZFIN:ZDB-PUB-070523-16
  3. 3.0 3.1 3.2 3.3 3.4 3.5 Mintzer, KA et al. (2001) Lost-a-fin encodes a type I BMP receptor, Alk8, acting maternally and zygotically in dorsoventral pattern formation. Development 128 859-69 PubMed GONUTS page ZFIN:ZDB-PUB-010306-4
  4. Chocron, S et al. (2007) Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. Dev. Biol. 305 577-88 PubMed GONUTS page ZFIN:ZDB-PUB-070409-7
  5. 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 ZFIN:ZDB-PUB-020724-1 ZFIN:ZDB-PUB-020724-1
  6. 6.0 6.1 6.2 Yelick, PC et al. (1998) zALK-8, a novel type I serine/threonine kinase receptor, is expressed throughout early zebrafish development. Dev. Dyn. 211 352-61 PubMed GONUTS page ZFIN:ZDB-PUB-980421-7
  7. 7.0 7.1 Payne-Ferreira, TL et al. (2004) Maternal alk8 promoter fragment directs expression in early oocytes. Zebrafish 1 27-39 PubMed GONUTS page ZFIN:ZDB-PUB-040521-3
  8. 8.0 8.1 Chen, JN et al. (1997) Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development 124 4373-82 PubMed GONUTS page ZFIN:ZDB-PUB-971203-9
  9. 9.0 9.1 9.2 Payne-Ferreira, TL & Yelick, PC (2003) Alk8 is required for neural crest cell formation and development of pharyngeal arch cartilages. Dev. Dyn. 228 683-96 PubMed GONUTS page ZFIN:ZDB-PUB-031204-7
  10. Locascio, A et al. (2002) Modularity and reshuffling of Snail and Slug expression during vertebrate evolution. Proc. Natl. Acad. Sci. U.S.A. 99 16841-6 PubMed GONUTS page ZFIN:ZDB-PUB-040103-1
  11. 11.0 11.1 11.2 11.3 11.4 Payne, TL et al. (2001) Functional characterization and genetic mapping of alk8. Mech. Dev. 100 275-89 PubMed GONUTS page ZFIN:ZDB-PUB-010219-14
  12. Wagner, DS & Mullins, MC (2002) Modulation of BMP activity in dorsal-ventral pattern formation by the chordin and ogon antagonists. Dev. Biol. 245 109-23 PubMed GONUTS page ZFIN:ZDB-PUB-020605-7
  13. 13.0 13.1 13.2 Sidi, S et al. (2003) Maternal induction of ventral fate by zebrafish radar. Proc. Natl. Acad. Sci. U.S.A. 100 3315-20 PubMed GONUTS page ZFIN:ZDB-PUB-030304-6
  14. Reim, G & Brand, M (2006) Maternal control of vertebrate dorsoventral axis formation and epiboly by the POU domain protein Spg/Pou2/Oct4. Development 133 2757-70 PubMed GONUTS page ZFIN:ZDB-PUB-060616-57
  15. Smith, KA et al. (2008) Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells. Dev. Cell 14 287-97 PubMed GONUTS page ZFIN:ZDB-PUB-080309-9
  16. 16.0 16.1 Hogan, BM et al. (2006) Specification of the primitive myeloid precursor pool requires signaling through Alk8 in zebrafish. Curr. Biol. 16 506-11 PubMed GONUTS page ZFIN:ZDB-PUB-060315-18
  17. Payne, TL et al. (2001) Regulation of tooth development by the novel type I TGFbeta family member receptor Alk8. J. Dent. Res. 80 1968-73 PubMed GONUTS page ZFIN:ZDB-PUB-020107-2
  18. Perrino, MA & Yelick, PC (2004) Immunolocalization of Alk8 during replacement tooth development in zebrafish. Cells Tissues Organs (Print) 176 17-27 PubMed GONUTS page ZFIN:ZDB-PUB-040204-4
  19. 19.0 19.1 19.2 von der Hardt, S et al. (2007) The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Curr. Biol. 17 475-87 PubMed GONUTS page ZFIN:ZDB-PUB-070303-41
  20. 20.0 20.1 20.2 20.3 Bauer, H et al. (2001) The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo. Development 128 849-58 PubMed GONUTS page ZFIN:ZDB-PUB-010306-5
  21. Mullins, MC et al. (1996) Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes. Development 123 81-93 PubMed GONUTS page ZFIN:ZDB-PUB-970210-7