YERPG:A9R4C4

Species (Taxon ID)	Yersinia pestis bv. Antiqua (strain Angola). (349746)
Gene Name(s)	ompR (ECO:0000313 with EMBL:ABX87158.1)
Protein Name(s)	Transcriptional regulatory protein OmpR (ECO:0000313 with EMBL:ABX87158.1)
External Links
UniProt	A9R4C4
EMBL	CP000901
RefSeq	YP_001608057.1
ProteinModelPortal	A9R4C4
STRING	349746.YpAngola_A3741
EnsemblBacteria	ABX87158
GeneID	5802218
KEGG	ypg:YpAngola_A3741
PATRIC	18577181
eggNOG	COG0745
HOGENOM	HOG000034819
KO	K07659
OMA	REPMSRD
OrthoDB	EOG6G4VQG
BioCyc	YPES349746:GHPB-3751-MONOMER
Proteomes	UP000001204
GO	GO:0003677 GO:0000160 GO:0006355 GO:0006351
Gene3D	1.10.10.10
InterPro	IPR011006 IPR001867 IPR016032 IPR001789 IPR011991
Pfam	PF00072 PF00486
SMART	SM00448 SM00862
SUPFAM	SSF46894 SSF52172
PROSITE	PS50110

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0090046	regulation of transcription regulator activity	PMID:21345178	IMP: Inferred from Mutant Phenotype		P	OmpR was found to have an effect on 224 genes based on cDNA microarray data, representing 4% of the proteins in the cell. 16 genes were validated to have OmpR-dependent transcription, including ompR, ompC, ompF, and ompX, which were further classified. Figure 2 gives a comparison of mRNA levels between WT and ompR mutant using RT-PCR and LacZ fusion. OmpC, ompF, and ompZ show between a 3 and 25-fold decrease in expression in the mutant.	complete
	GO:0000156	phosphorelay response regulator activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001789 InterPro:IPR001867	F	Seeded From UniProt	complete
	GO:0000160	phosphorelay signal transduction system	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001789 InterPro:IPR001867	P	Seeded From UniProt	complete
	GO:0006950	response to stress	PMID:21345178	IMP: Inferred from Mutant Phenotype		P	Figure 1 shows a decreased survival when exposed to high osmolarity, high temperature, and low pH for the ompR mutant as well as a higher rate of phagocytosis.	complete
	GO:0000160	phosphorelay signal transduction system	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0902	P	Seeded From UniProt	complete
	GO:0003677	DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001867	F	Seeded From UniProt	complete
	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001789 InterPro:IPR001867	P	Seeded From UniProt	complete
	GO:0035556	intracellular signal transduction	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001789 InterPro:IPR001867	P	Seeded From UniProt	complete
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References

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