YERPE:A0A384L3J4

Species (Taxon ID)	Yersinia pestis. (632)
Gene Name(s)	cap (ECO:0000313 with EMBL:CAL18860.1)
Protein Name(s)	cAMP-activated global transcriptional regulator CRP (ECO:0000313 with EMBL:PWF35750.1) cAMP-regulatory protein (ECO:0000313 with EMBL:CAL18860.1)
External Links
UniProt	A0A384L3J4
EMBL	AL590842 QANK01000056
PIR	AC0022
RefSeq	WP_002212297.1 YP_002345259.1
PDB	6DT4
PDBsum	6DT4
DNASU	1148903
GeneID	1173020 31911418
KEGG	ype:YPO0175 ypj:CH55_2915 ypl:CH46_741 ypv:BZ15_3396 ypw:CH59_2267
PATRIC	fig|1028802.3.peg.174
eggNOG	ENOG4107RYR COG0664
HOGENOM	HOG000250565
KO	K10914
Proteomes	UP000000815
CollecTF	EXPREG_00000ff0
GO	GO:0003677 GO:0003700
CDD	cd00038
Gene3D	1.10.10.10 2.60.120.10
InterPro	IPR018490 IPR018488 IPR000595 IPR012318 IPR014710 IPR018335 IPR036388 IPR036390
Pfam	PF00027 PF13545
PRINTS	PR00034
SMART	SM00100 SM00419
SUPFAM	SSF46785 SSF51206
PROSITE	PS00888 PS00889 PS50042 PS00042 PS51063

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012318	F		Seeded From UniProt
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR018335	F		Seeded From UniProt
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012318 InterPro:IPR018335	P		Seeded From UniProt
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012318	F		Seeded From UniProt
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR018335	F		Seeded From UniProt
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012318 InterPro:IPR018335	P		Seeded From UniProt
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt
	GO:0045892	negative regulation of transcription, DNA-templated	PMID:19703315	ECO:0005657	primer extension assay evidence used in manual assertion		P		Figure 5 shows the primer extension analysis of the sycO-ypkA-yopJ operon with and without CRP. A wild type with CRP and a strain without CRP were used. The WT shows no primer extension product while the strain without CRP shows product. The presence of the primer extension product in deleted CRP indicates mRNA presence. The lack of primer extension product in the WT indicates no mRNA presence. Because mRNA presence is high only in the deleted CRP strain, CRP is repressing transcription of the sycO-ypkA-yopJ operon.	complete CACAO 13723
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References

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