GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

YEAST:VPS74

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) VPS74
Protein Name(s) Vacuolar protein sorting-associated protein 74
External Links
UniProt Q06385
EMBL U28373
BK006938
PIR S61167
RefSeq NP_010660.1
PDB 2ZIH
2ZII
4TU3
PDBsum 2ZIH
2ZII
4TU3
ProteinModelPortal Q06385
SMR Q06385
BioGrid 32431
DIP DIP-1768N
IntAct Q06385
MINT MINT-411600
STRING 4932.YDR372C
MaxQB Q06385
PaxDb Q06385
PeptideAtlas Q06385
EnsemblFungi [example_ID YDR372C]
GeneID 851978
KEGG sce:YDR372C
CYGD YDR372c
SGD S000002780
eggNOG NOG79916
GeneTree ENSGT00390000007153
HOGENOM HOG000209848
InParanoid Q06385
KO K15620
OMA VMKIGFQ
OrthoDB EOG7VTDXX
BioCyc YEAST:G3O-29922-MONOMER
EvolutionaryTrace Q06385
NextBio 970118
Proteomes UP000002311
Genevestigator Q06385
GO GO:0005829
GO:0019898
GO:0005794
GO:0032580
GO:0005797
GO:0019899
GO:0070273
GO:0030968
GO:0034067
GO:0015031
GO:0060304
GO:0006890
InterPro IPR008628
PANTHER PTHR12704
Pfam PF05719

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005794

Golgi apparatus

PMID:24019977[1]

ECO:0000314

C

Figure 2 and Table 2 show the results from an immunofluorescence assay.

complete
CACAO 10429

GO:0005802

trans-Golgi network

PMID:19837035[2]

ECO:0000314

C

Figure S2B shows the vps74 colocalizes to the trans-golgi

complete
CACAO 9715

GO:0006487

protein N-linked glycosylation

PMID:18410729[3]

ECO:0000315

P

Figure 1. KOs of the vps74 result in lack of mannosylation of various proteins

complete
CACAO 9716

GO:0035269

protein O-linked mannosylation

PMID:18410729[3]

ECO:0000315

P

Figure 1: KOs of vps74 result in lack of mannosylation of various proteins

complete
CACAO 9717

part_of

GO:0005634

nucleus

PMID:14562095[4]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:14562095[4]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0035269

protein O-linked mannosylation

PMID:18410729[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006487

protein N-linked glycosylation

PMID:18410729[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005802

trans-Golgi network

PMID:19837035[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0070273

phosphatidylinositol-4-phosphate binding

PMID:20026658[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0070273

phosphatidylinositol-4-phosphate binding

PMID:20026658[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0060304

regulation of phosphatidylinositol dephosphorylation

PMID:22553352[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

UniProtKB:P32368

P

Seeded From UniProt

complete

involved_in

GO:0034067

protein localization to Golgi apparatus

PMID:18410729[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030968

endoplasmic reticulum unfolded protein response

PMID:16582425[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0019899

enzyme binding

PMID:18410729[3]

ECO:0000353

physical interaction evidence used in manual assertion

SGD:S000000219
SGD:S000002891
SGD:S000003006
SGD:S000003722

F

Seeded From UniProt

complete

part_of

GO:0019898

extrinsic component of membrane

PMID:18635803[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006890

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

PMID:18635803[8]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18410729[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005797

Golgi medial cisterna

PMID:22553352[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:18410729[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0070273

phosphatidylinositol-4-phosphate binding

PMID:19837035[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:19837035[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0070273

phosphatidylinositol-4-phosphate binding

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000294961
SGD:S000002780
UniProtKB:Q9H4A5
UniProtKB:Q9H4A6

F

Seeded From UniProt

complete

involved_in

GO:0048194

Golgi vesicle budding

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000294961
UniProtKB:Q9H4A6

P

Seeded From UniProt

complete

involved_in

GO:0043001

Golgi to plasma membrane protein transport

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000294961
UniProtKB:Q9H4A6

P

Seeded From UniProt

complete

part_of

GO:0031985

Golgi cisterna

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000294961
UniProtKB:Q9H4A6

C

Seeded From UniProt

complete

involved_in

GO:0007030

Golgi organization

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000294961
UniProtKB:Q9H4A5
UniProtKB:Q9H4A6

P

Seeded From UniProt

complete

involved_in

GO:0006890

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000294961
SGD:S000002780

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000294961
RGD:621226
SGD:S000002780
UniProtKB:Q9H4A6

C

Seeded From UniProt

complete

part_of

GO:0005802

trans-Golgi network

PMID:21873635[9]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000294961
RGD:621226
UniProtKB:Q9H4A6

C

Seeded From UniProt

complete

enables

GO:0070273

phosphatidylinositol-4-phosphate binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008628

F

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333

C

Seeded From UniProt

complete

enables

GO:0008289

lipid binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0446

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0032580

Golgi cisterna membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0136

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Hsu, JW et al. (2013) The N-terminus of Vps74p is essential for the retention of glycosyltransferases in the Golgi but not for the modulation of apical polarized growth in Saccharomyces cerevisiae. PLoS ONE 8 e74715 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 Dippold, HC et al. (2009) GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote budding. Cell 139 337-51 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Schmitz, KR et al. (2008) Golgi localization of glycosyltransferases requires a Vps74p oligomer. Dev. Cell 14 523-34 PubMed GONUTS page
  4. ↑ 4.0 4.1 Huh, WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425 686-91 PubMed GONUTS page
  5. ↑ 5.0 5.1 Wood, CS et al. (2009) PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking. J. Cell Biol. 187 967-75 PubMed GONUTS page
  6. ↑ 6.0 6.1 Wood, CS et al. (2012) Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase. Mol. Biol. Cell 23 2527-36 PubMed GONUTS page
  7. ↑ Hancock, LC et al. (2006) Genomic analysis of the Opi- phenotype. Genetics 173 621-34 PubMed GONUTS page
  8. ↑ 8.0 8.1 Tu, L et al. (2008) Signal-mediated dynamic retention of glycosyltransferases in the Golgi. Science 321 404-7 PubMed GONUTS page
  9. ↑ 9.0 9.1 9.2 9.3 9.4 9.5 9.6 9.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=YEAST:VPS74&oldid=5959386"