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YEAST:UBX1
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | SHP1 (synonyms: UBX1) | |
| Protein Name(s) | UBX domain-containing protein 1
Suppressor of high-copy PP1 protein | |
| External Links | ||
| UniProt | P34223 | |
| EMBL | Z23261 Z35819 AY557717 BK006936 | |
| PIR | S39830 | |
| RefSeq | NP_009495.1 | |
| ProteinModelPortal | P34223 | |
| SMR | P34223 | |
| BioGrid | 32641 | |
| DIP | DIP-2789N | |
| IntAct | P34223 | |
| MINT | MINT-656846 | |
| iPTMnet | P34223 | |
| MaxQB | P34223 | |
| PRIDE | P34223 | |
| TopDownProteomics | P34223 | |
| EnsemblFungi | YBL058W | |
| GeneID | 852222 | |
| KEGG | sce:YBL058W | |
| EuPathDB | FungiDB:YBL058W | |
| SGD | S000000154 | |
| GeneTree | ENSGT00520000055567 | |
| HOGENOM | HOG000159961 | |
| KO | K14012 | |
| OMA | RENDERW | |
| OrthoDB | EOG092C45A0 | |
| BioCyc | YEAST:G3O-28956-MONOMER | |
| PRO | PR:P34223 | |
| Proteomes | UP000002311 | |
| GO | GO:0005737 GO:0005634 GO:0019888 GO:0043130 GO:0030437 GO:0000045 GO:0005977 GO:0007030 GO:0061025 GO:0031468 GO:0034727 GO:0043161 GO:0031134 GO:0030433 | |
| InterPro | IPR012989 IPR029071 IPR001012 | |
| Pfam | PF08059 PF00789 | |
| SMART | SM00553 SM00166 | |
| SUPFAM | SSF102848 SSF54236 | |
| PROSITE | PS51399 PS50033 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0016049 |
cell growth |
ECO:0000315 |
P |
Figure 1 Demonstrates that when SHP1 gene is mutated, cell growth is is defected and there is a delay in the cell cycle. UBX domain-containing protein 1 Saccharomyces cerevisiae |
complete | |||||
|
part_of |
GO:0005829 |
cytosol |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043161 |
proteasome-mediated ubiquitin-dependent protein catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034727 |
piecemeal microautophagy of the nucleus |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031134 |
sister chromatid biorientation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030437 |
ascospore formation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030433 |
ubiquitin-dependent ERAD pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019888 |
protein phosphatase regulator activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019888 |
protein phosphatase regulator activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0005977 |
glycogen metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000045 |
autophagosome assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061025 |
membrane fusion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000596257 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043161 |
proteasome-mediated ubiquitin-dependent protein catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000596256 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0043130 |
ubiquitin binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000596256 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0031468 |
nuclear envelope reassembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0033179 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007030 |
Golgi organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000596257 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2442310 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000045 |
autophagosome assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000596257 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043666 |
regulation of phosphoprotein phosphatase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0019888 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043666 |
regulation of phosphoprotein phosphatase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0019888 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Böhm, S & Buchberger, A (2013) The budding yeast Cdc48(Shp1) complex promotes cell cycle progression by positive regulation of protein phosphatase 1 (Glc7). PLoS ONE 8 e56486 PubMed GONUTS page
- ↑ 2.0 2.1 Yofe, I et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat. Methods 13 371-378 PubMed GONUTS page
- ↑ 3.0 3.1 Huh, WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425 686-91 PubMed GONUTS page
- ↑ Schuberth, C et al. (2004) Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation. EMBO Rep. 5 818-24 PubMed GONUTS page
- ↑ 5.0 5.1 Krick, R et al. (2010) Cdc48/p97 and Shp1/p47 regulate autophagosome biogenesis in concert with ubiquitin-like Atg8. J. Cell Biol. 190 965-73 PubMed GONUTS page
- ↑ Cheng, YL & Chen, RH (2010) The AAA-ATPase Cdc48 and cofactor Shp1 promote chromosome bi-orientation by balancing Aurora B activity. J. Cell. Sci. 123 2025-34 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Zhang, S et al. (1995) The Saccharomyces SHP1 gene, which encodes a regulator of phosphoprotein phosphatase 1 with differential effects on glycogen metabolism, meiotic differentiation, and mitotic cell cycle progression. Mol. Cell. Biol. 15 2037-50 PubMed GONUTS page
- ↑ Tran, JR et al. (2011) A Cdc48p-associated factor modulates endoplasmic reticulum-associated degradation, cell stress, and ubiquitinated protein homeostasis. J. Biol. Chem. 286 5744-55 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 9.4 9.5 9.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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