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YEAST:SNU66

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) SNU66
Protein Name(s) 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component
External Links
UniProt Q12420
EMBL X90565
Z75216
BK006948
PIR S58319
RefSeq NP_014953.3
PDB 3PLU
3PLV
PDBsum 3PLU
3PLV
ProteinModelPortal Q12420
BioGrid 34697
DIP DIP-5216N
IntAct Q12420
MINT MINT-519249
STRING 4932.YOR308C
MaxQB Q12420
PaxDb Q12420
EnsemblFungi [example_ID YOR308C]
GeneID 854485
KEGG sce:YOR308C
CYGD YOR308c
SGD S000005835
eggNOG NOG268163
InParanoid Q12420
KO K11984
OMA EETNEIR
OrthoDB EOG74N5S1
BioCyc YEAST:G3O-33792-MONOMER
NextBio 976807
PRO PR:Q12420
Proteomes UP000002311
Genevestigator Q12420
GO GO:0005681
GO:0046540
GO:0000481
GO:0000398
InterPro IPR005011
PANTHER PTHR14152
Pfam PF03343

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005634

nucleus

PMID:15620657[1]

ECO:0000314

C

Figure S4 of the supplementary data indicates nuclear localization of Snu66 in S. cerevisiae.

complete
CACAO 8605

part_of

GO:0005634

nucleus

PMID:15620657[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0046540

U4/U6 x U5 tri-snRNP complex

PMID:10377396[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0046540

U4/U6 x U5 tri-snRNP complex

PMID:10449419[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003674

molecular_function

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0000481

maturation of 5S rRNA

PMID:19806183[4]

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000003508

P

Seeded From UniProt

complete

involved_in

GO:0000481

maturation of 5S rRNA

PMID:19806183[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000398

mRNA splicing, via spliceosome

PMID:10377396[2]

ECO:0000353

physical interaction evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000398

mRNA splicing, via spliceosome

PMID:11720284[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000398

mRNA splicing, via spliceosome

PMID:10449419[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0046540

U4/U6 x U5 tri-snRNP complex

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000365724
PomBase:SPAC167.03c
SGD:S000005835

C

Seeded From UniProt

complete

involved_in

GO:0045292

mRNA cis splicing, via spliceosome

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000365724
PomBase:SPAC167.03c

P

Seeded From UniProt

complete

involved_in

GO:0000481

maturation of 5S rRNA

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000365724
SGD:S000005835

P

Seeded From UniProt

complete

involved_in

GO:0000398

mRNA splicing, via spliceosome

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005011

P

Seeded From UniProt

complete

involved_in

GO:0006397

mRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0507

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005681

spliceosomal complex

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0747

C

Seeded From UniProt

complete

involved_in

GO:0008380

RNA splicing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0508

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Wilkinson, CR et al. (2004) Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast. Curr. Biol. 14 2283-8 PubMed GONUTS page
  2. 2.0 2.1 Stevens, SW & Abelson, J (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc. Natl. Acad. Sci. U.S.A. 96 7226-31 PubMed GONUTS page
  3. 3.0 3.1 Gottschalk, A et al. (1999) Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP. EMBO J. 18 4535-48 PubMed GONUTS page
  4. 4.0 4.1 Li, Z et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol. 7 e1000213 PubMed GONUTS page
  5. Stevens, SW et al. (2001) Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA 7 1543-53 PubMed GONUTS page
  6. 6.0 6.1 6.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page