GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

YEAST:SEC7

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) SEC7
Protein Name(s) Protein transport protein SEC7
External Links
UniProt P11075
EMBL J03918
Z46727
Z47813
BK006938
PIR S49764
RefSeq NP_010454.3
PDB 4OIY
PDBsum 4OIY
ProteinModelPortal P11075
SMR P11075
BioGrid 32221
DIP DIP-830N
IntAct P11075
MINT MINT-616341
MaxQB P11075
PaxDb P11075
PeptideAtlas P11075
PRIDE P11075
EnsemblFungi [example_ID YDR170C]
GeneID 851748
KEGG sce:YDR170C
CYGD YDR170c
SGD S000002577
eggNOG COG5307
GeneTree ENSGT00760000119036
HOGENOM HOG000181045
InParanoid P11075
KO K18442
OMA ICECFEN
OrthoDB EOG725DRW
BioCyc YEAST:G3O-29759-MONOMER
NextBio 969499
PRO PR:P11075
Proteomes UP000002311
Genevestigator P11075
GO GO:0005829
GO:0005798
GO:0005770
GO:0005802
GO:0005086
GO:0000045
GO:0006888
GO:0006891
GO:0043547
GO:0015031
GO:0032012
Gene3D 1.10.1000.11
InterPro IPR016024
IPR015403
IPR023394
IPR000904
Pfam PF09324
PF01369
SMART SM00222
SUPFAM SSF48371
SSF48425
PROSITE PS50190

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0000138

Golgi trans cisterna

PMID:19837035[1]

ECO:0000314

C

Figure S2B - Sec7 is used as an agent indicating colocalization to trans-golgi

complete
CACAO 9720

involved_in

GO:0006891

intra-Golgi vesicle-mediated transport

PMID:3042778[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006888

endoplasmic reticulum to Golgi vesicle-mediated transport

PMID:9473503[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:1986005[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005802

trans-Golgi network

PMID:1986005[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005798

Golgi-associated vesicle

PMID:1729652[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005770

late endosome

PMID:12006663[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005086

ARF guanyl-nucleotide exchange factor activity

PMID:10430582[7]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005086

ARF guanyl-nucleotide exchange factor activity

PMID:9539714[8]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0000045

autophagosome assembly

PMID:20444982[9]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0016192

vesicle-mediated transport

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000070561
TAIR:locus:2025502
TAIR:locus:2084706

P

Seeded From UniProt

complete

part_of

GO:0005802

trans-Golgi network

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0028538
PANTHER:PTN000070561
RGD:1560793
RGD:631430
SGD:S000002577
TAIR:locus:2084706

C

Seeded From UniProt

complete

enables

GO:0005086

ARF guanyl-nucleotide exchange factor activity

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0028538
PANTHER:PTN000070561
SGD:S000002577
UniProtKB:Q9Y6D5

F

Seeded From UniProt

complete

enables

GO:0005086

ARF guanyl-nucleotide exchange factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000904
InterPro:IPR035999

F

Seeded From UniProt

complete

involved_in

GO:0032012

regulation of ARF protein signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000904
InterPro:IPR035999

P

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333
UniProtKB-SubCell:SL-0132

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Dippold, HC et al. (2009) GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote budding. Cell 139 337-51 PubMed GONUTS page
  2. Achstetter, T et al. (1988) SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus. J. Biol. Chem. 263 11711-7 PubMed GONUTS page
  3. Wolf, J et al. (1998) An N-end rule destabilization mutant reveals pre-Golgi requirements for Sec7p in yeast membrane traffic. Biochem. Biophys. Res. Commun. 243 191-8 PubMed GONUTS page
  4. 4.0 4.1 Franzusoff, A et al. (1991) Localization of components involved in protein transport and processing through the yeast Golgi apparatus. J. Cell Biol. 112 27-37 PubMed GONUTS page
  5. Franzusoff, A et al. (1992) Immuno-isolation of Sec7p-coated transport vesicles from the yeast secretory pathway. Nature 355 173-5 PubMed GONUTS page
  6. Belgareh-Touzé, N et al. (2002) Yeast Vps55p, a functional homolog of human obesity receptor gene-related protein, is involved in late endosome to vacuole trafficking. Mol. Biol. Cell 13 1694-708 PubMed GONUTS page
  7. Jones, S et al. (1999) Genetic interactions in yeast between Ypt GTPases and Arf guanine nucleotide exchangers. Genetics 152 1543-56 PubMed GONUTS page
  8. Sata, M et al. (1998) Brefeldin A-inhibited guanine nucleotide-exchange activity of Sec7 domain from yeast Sec7 with yeast and mammalian ADP ribosylation factors. Proc. Natl. Acad. Sci. U.S.A. 95 4204-8 PubMed GONUTS page
  9. van der Vaart, A et al. (2010) Exit from the Golgi is required for the expansion of the autophagosomal phagophore in yeast Saccharomyces cerevisiae. Mol. Biol. Cell 21 2270-84 PubMed GONUTS page
  10. 10.0 10.1 10.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page