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YEAST:RFM1

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) RFM1
Protein Name(s) Repression factor of MSEs protein 1
External Links
UniProt Q12192
EMBL X89633
Z75187
BK006948
PIR S67181
RefSeq NP_014922.3
ProteinModelPortal Q12192
BioGrid 34667
ComplexPortal CPX-1384
DIP DIP-4430N
IntAct Q12192
MINT Q12192
STRING 4932.YOR279C
CarbonylDB Q12192
iPTMnet Q12192
PaxDb Q12192
PRIDE Q12192
EnsemblFungi YOR279C
GeneID 854453
KEGG sce:YOR279C
SGD S000005805
InParanoid Q12192
OMA FESYQDY
OrthoDB EOG092C5NXF
BioCyc YEAST:G3O-33766-MONOMER
PRO PR:Q12192
Proteomes UP000002311
GO GO:0000118
GO:0005634
GO:0030674
GO:0000122
GO:0032298
InterPro IPR020318
ProDom PD063974

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0051038

negative regulation of transcription involved in meiotic cell cycle

PMID:12612074[1]

ECO:0000315

P

Fig 1. Shows that in S. cerevisiae, the rfm1 gene is required for repressing the expression of S. cerevisiae middle class sporulation elements.

complete
CACAO 13420

involved_in

GO:0032298

positive regulation of DNA-dependent DNA replication initiation

PMID:18990212[2]

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000000264

P

Seeded From UniProt

complete

enables

GO:0030674

protein binding, bridging

PMID:12612074[1]

ECO:0000353

physical interaction evidence used in manual assertion

SGD:S000002718
SGD:S000005429

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:12612074[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

happens_during:(GO:0000278)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:11711434[3]

ECO:0000353

physical interaction evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0000118

histone deacetylase complex

PMID:12612074[1]

ECO:0000353

physical interaction evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 McCord, R et al. (2003) Rfm1, a novel tethering factor required to recruit the Hst1 histone deacetylase for repression of middle sporulation genes. Mol. Cell. Biol. 23 2009-16 PubMed GONUTS page
  2. Weber, JM et al. (2008) Control of replication initiation by the Sum1/Rfm1/Hst1 histone deacetylase. BMC Mol. Biol. 9 100 PubMed GONUTS page
  3. Pijnappel, WW et al. (2001) The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev. 15 2991-3004 PubMed GONUTS page