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YEAST:NHP10

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) NHP10 (synonyms: HMO2)
Protein Name(s) Non-histone protein 10

High mobility group protein 2

External Links
UniProt Q03435
EMBL Z48008
BK006938
PIR S50980
RefSeq NP_010282.3
ProteinModelPortal Q03435
SMR Q03435
BioGrid 32052
DIP DIP-1387N
IntAct Q03435
MINT MINT-388714
STRING 4932.YDL002C
MaxQB Q03435
PaxDb Q03435
PeptideAtlas Q03435
EnsemblFungi [example_ID YDL002C]
GeneID 851562
KEGG sce:YDL002C
CYGD YDL002c
SGD S000002160
eggNOG COG5648
HOGENOM HOG000001026
InParanoid Q03435
KO K11680
OMA AYLLFCE
OrthoDB EOG70KH25
BioCyc YEAST:G3O-29433-MONOMER
NextBio 968998
Proteomes UP000002311
Genevestigator Q03435
GO GO:0031011
GO:0045027
GO:0000404
GO:0006302
GO:0042766
GO:0006355
GO:0000722
GO:0006351
Gene3D 1.10.30.10
InterPro IPR009071
Pfam PF00505
SMART SM00398
SUPFAM SSF47095
PROSITE PS50118

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005634

nucleus

PMID:14562095[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0045027

DNA end binding

PMID:19726587[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0042766

nucleosome mobilization

PMID:12887900[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0031011

Ino80 complex

PMID:24034245[4]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P53115

C

Seeded From UniProt

complete

part_of

GO:0031011

Ino80 complex

PMID:12887900[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006302

double-strand break repair

PMID:15607974[5]

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000002217

P

Seeded From UniProt

complete

involved_in

GO:0006302

double-strand break repair

PMID:17762868[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000722

telomere maintenance via recombination

PMID:23390378[7]

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000006657

P

Seeded From UniProt

complete

enables

GO:0000404

heteroduplex DNA loop binding

PMID:19726587[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008301

DNA binding, bending

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004362
FB:FBgn0278608
PANTHER:PTN000345179
RGD:2802
SGD:S000002157
SGD:S000004676
SGD:S000006256
UniProtKB:F1RJ01
UniProtKB:F2Z594
UniProtKB:P09429
UniProtKB:P10103
UniProtKB:P12682
UniProtKB:P17741
UniProtKB:P26583
UniProtKB:P26584
UniProtKB:P40618
UniProtKB:P40673
UniProtKB:Q32L31
UniProtKB:Q8I616
UniProtKB:Q8IB14
UniProtKB:Q9YH06

F

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0278608
MGI:MGI:96157
PANTHER:PTN000345179
RGD:2802
UniProtKB:P09429

F

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0278608
MGI:MGI:96113
MGI:MGI:96157
PANTHER:PTN000346026
UniProtKB:P09429
UniProtKB:P26583
WB:WBGene00001972

P

Seeded From UniProt

complete

involved_in

GO:0006338

chromatin remodeling

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000345179
SGD:S000002157
SGD:S000006256

P

Seeded From UniProt

complete

part_of

GO:0000790

nuclear chromatin

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96157
PANTHER:PTN000346026
SGD:S000002160
UniProtKB:F1RJ01
UniProtKB:F2Z594
UniProtKB:P12682
UniProtKB:P17741

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Huh, WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425 686-91 PubMed GONUTS page
  2. 2.0 2.1 Ray, S & Grove, A (2009) The yeast high mobility group protein HMO2, a subunit of the chromatin-remodeling complex INO80, binds DNA ends. Nucleic Acids Res. 37 6389-99 PubMed GONUTS page
  3. 3.0 3.1 Shen, X et al. (2003) Involvement of actin-related proteins in ATP-dependent chromatin remodeling. Mol. Cell 12 147-55 PubMed GONUTS page
  4. Tosi, A et al. (2013) Structure and subunit topology of the INO80 chromatin remodeler and its nucleosome complex. Cell 154 1207-19 PubMed GONUTS page
  5. Morrison, AJ et al. (2004) INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell 119 767-75 PubMed GONUTS page
  6. van Attikum, H et al. (2007) Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks. EMBO J. 26 4113-25 PubMed GONUTS page
  7. Hu, Y et al. (2013) Telomerase-null survivor screening identifies novel telomere recombination regulators. PLoS Genet. 9 e1003208 PubMed GONUTS page
  8. 8.0 8.1 8.2 8.3 8.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page