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YEAST:HSP74
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | SSA4 | |
| Protein Name(s) | Heat shock protein SSA4 | |
| External Links | ||
| UniProt | P22202 | |
| EMBL | J05637 U18839 BK006939 | |
| PIR | B36590 | |
| RefSeq | NP_011029.3 | |
| PDB | 3UPV | |
| PDBsum | 3UPV | |
| ProteinModelPortal | P22202 | |
| SMR | P22202 | |
| BioGrid | 36849 | |
| DIP | DIP-3916N | |
| IntAct | P22202 | |
| MINT | MINT-523139 | |
| STRING | 4932.YER103W | |
| MaxQB | P22202 | |
| PaxDb | P22202 | |
| PeptideAtlas | P22202 | |
| PRIDE | P22202 | |
| EnsemblFungi | [example_ID YER103W] | |
| GeneID | 856840 | |
| KEGG | sce:YER103W | |
| SGD | S000000905 | |
| eggNOG | COG0443 | |
| GeneTree | ENSGT00740000115745 | |
| HOGENOM | HOG000228135 | |
| InParanoid | P22202 | |
| KO | K03283 | |
| OMA | MRNTIRE | |
| OrthoDB | EOG728916 | |
| BioCyc | YEAST:G3O-30268-MONOMER | |
| Reactome | REACT_205607 REACT_219346 REACT_271186 | |
| NextBio | 983153 | |
| Proteomes | UP000002311 | |
| Genevestigator | P22202 | |
| GO | GO:0005737 GO:0005634 GO:0005524 GO:0016887 GO:0051082 GO:0006200 GO:0034605 GO:0006457 GO:0006616 | |
| Gene3D | 1.20.1270.10 2.60.34.10 | |
| InterPro | IPR018181 IPR029048 IPR029047 IPR013126 | |
| Pfam | PF00012 | |
| PRINTS | PR00301 | |
| SUPFAM | SSF100920 SSF100934 | |
| PROSITE | PS00297 PS00329 PS01036 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0051082 |
unfolded protein binding |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000000004 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0051082 |
unfolded protein binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
| GO:0009408 |
response to heat |
22579450:22579450 |
ECO:0000314 |
P |
Figure 3 represents assays on the amount of the protein present after heat was applied. Expression was measured using RNeasy Mini Kit. Selected primers were seen in table 1 |
complete | ||||
|
involved_in |
GO:0034605 |
cellular response to heat |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016887 |
ATPase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006616 |
SRP-dependent cotranslational protein targeting to membrane, translocation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006457 |
protein folding |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000000004 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016887 |
ATPase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10241 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016192 |
vesicle-mediated transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0266599 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006986 |
response to unfolded protein |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002321897 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006616 |
SRP-dependent cotranslational protein targeting to membrane, translocation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001065101 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000184853 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000184706 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10241 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0266599 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10241 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0051787 |
misfolded protein binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:95835 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051085 |
chaperone cofactor-dependent protein refolding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10241 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0051082 |
unfolded protein binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10241 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0044183 |
protein folding chaperone |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10241 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042623 |
ATPase activity, coupled |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:105384 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042026 |
protein refolding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002321897 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0034620 |
cellular response to unfolded protein |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10241 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0034605 |
cellular response to heat |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000184706 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0031072 |
heat shock protein binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002321897 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Kim, S et al. (1998) Folding in vivo of a newly translated yeast cytosolic enzyme is mediated by the SSA class of cytosolic yeast Hsp70 proteins. Proc. Natl. Acad. Sci. U.S.A. 95 12860-5 PubMed GONUTS page
- ↑ 2.0 2.1 Boorstein, WR et al. (1994) Molecular evolution of the HSP70 multigene family. J. Mol. Evol. 38 1-17 PubMed GONUTS page
- ↑ Boorstein, WR & Craig, EA (1990) Structure and regulation of the SSA4 HSP70 gene of Saccharomyces cerevisiae. J. Biol. Chem. 265 18912-21 PubMed GONUTS page
- ↑ Becker, J et al. (1996) Functional interaction of cytosolic hsp70 and a DnaJ-related protein, Ydj1p, in protein translocation in vivo. Mol. Cell. Biol. 16 4378-86 PubMed GONUTS page
- ↑ 5.0 5.1 Chughtai, ZS et al. (2001) Starvation promotes nuclear accumulation of the hsp70 Ssa4p in yeast cells. J. Biol. Chem. 276 20261-6 PubMed GONUTS page
- ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 6.13 6.14 6.15 6.16 6.17 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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