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YEAST:HED1

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) HED1
Protein Name(s) Meiosis-specific protein HED1

RED1 suppressor protein 1

External Links
UniProt Q03937
EMBL Z49770
BK006938
RefSeq NP_001035220.1
ProteinModelPortal Q03937
BioGrid 566604
PRIDE Q03937
EnsemblFungi YDR014W-A
GeneID 4036073
KEGG sce:YDR014W-A
EuPathDB FungiDB:YDR014W-A
SGD S000113613
InParanoid Q03937
OrthoDB EOG092652Y9
BioCyc YEAST:G3O-30129-MONOMER
PRO PR:Q03937
Proteomes UP000002311
GO GO:0000794
GO:0004857
GO:0006310
GO:0006281
GO:1903873
GO:0045950
GO:0007130

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0004857

enzyme inhibitor activity

PMID:27483004[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

regulates_activity_of:(UniProtKB:P25454)

Seeded From UniProt

complete

involved_in

GO:1903873

negative regulation of DNA recombinase mediator complex assembly

PMID:18347097[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007130

synaptonemal complex assembly

PMID:24367271[3]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:P25453

P

Seeded From UniProt

complete

involved_in

GO:0045950

negative regulation of mitotic recombination

PMID:16818607[4]

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000000981

P

Seeded From UniProt

complete

involved_in

GO:0045950

negative regulation of mitotic recombination

PMID:16818607[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045950

negative regulation of mitotic recombination

PMID:16818607[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004857

enzyme inhibitor activity

PMID:18347097[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0000794

condensed nuclear chromosome

PMID:16818607[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0043086

negative regulation of catalytic activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004857

P

Seeded From UniProt

complete

involved_in

GO:0043086

negative regulation of catalytic activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004857

P

Seeded From UniProt

complete

involved_in

GO:0006310

DNA recombination

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0233

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

part_of

GO:0005694

chromosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0158
UniProtKB-SubCell:SL-0468

C

Seeded From UniProt

complete

involved_in

GO:0051321

meiotic cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0469

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Callender, TL et al. (2016) Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1. PLoS Genet. 12 e1006226 PubMed GONUTS page
  2. 2.0 2.1 Busygina, V et al. (2008) Hed1 regulates Rad51-mediated recombination via a novel mechanism. Genes Dev. 22 786-95 PubMed GONUTS page
  3. Lao, JP et al. (2013) Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation. PLoS Genet. 9 e1003978 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Tsubouchi, H & Roeder, GS (2006) Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired. Genes Dev. 20 1766-75 PubMed GONUTS page