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YEAST:GAP1
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | GAP1 | |
| Protein Name(s) | General amino-acid permease GAP1 | |
| External Links | ||
| UniProt | P19145 | |
| EMBL | X52633 Z28264 AY723840 BK006944 | |
| PIR | S38111 | |
| RefSeq | NP_012965.3 | |
| ProteinModelPortal | P19145 | |
| SMR | P19145 | |
| BioGrid | 34171 | |
| DIP | DIP-8010N | |
| IntAct | P19145 | |
| MINT | MINT-1358192 | |
| STRING | 4932.YKR039W | |
| TCDB | 2.A.3.10.2 | |
| MaxQB | P19145 | |
| PaxDb | P19145 | |
| EnsemblFungi | [example_ID YKR039W] | |
| GeneID | 853912 | |
| KEGG | sce:YKR039W | |
| CYGD | YKR039w | |
| SGD | S000001747 | |
| eggNOG | COG0833 | |
| GeneTree | ENSGT00510000049744 | |
| HOGENOM | HOG000261848 | |
| InParanoid | P19145 | |
| KO | K16261 | |
| OMA | YGNQTVY | |
| OrthoDB | EOG74J9HZ | |
| BioCyc | YEAST:G3O-32011-MONOMER | |
| SABIO-RK | P19145 | |
| NextBio | 975250 | |
| Proteomes | UP000002311 | |
| Genevestigator | P19145 | |
| GO | GO:0005768 GO:0030134 GO:0000328 GO:0005887 GO:0005771 GO:0005886 GO:0015171 GO:0015193 GO:0015203 GO:0006865 GO:1902047 GO:0015846 GO:0035524 | |
| InterPro | IPR004841 IPR002293 IPR004762 IPR004840 | |
| PANTHER | PTHR11785 | |
| Pfam | PF00324 | |
| PIRSF | PIRSF006060 | |
| TIGRFAMs | TIGR00913 | |
| PROSITE | PS00218 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0015192 |
L-phenylalanine transmembrane transporter activity |
ECO:0000315 |
F |
Figure 1 shows phenylalanine transport in wild type cells grown on medium with proline as the sole nitrogen source is catalyzed by Gap1. Gap1 activity is absent when ammonium ion is used as a nitrogen source. |
complete | |||||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0001761 |
beta-alanine transmembrane transporter activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015192 |
L-phenylalanine transmembrane transporter activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030134 |
COPII-coated ER to Golgi transport vesicle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015846 |
polyamine transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015203 |
polyamine transmembrane transporter activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015193 |
L-proline transmembrane transporter activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000000530 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0015171 |
amino acid transmembrane transporter activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006865 |
amino acid transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005771 |
multivesicular body |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005768 |
endosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000328 |
fungal-type vacuole lumen |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001762 |
beta-alanine transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0001761 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0003333 |
amino acid transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015171 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0015823 |
phenylalanine transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015192 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035524 |
proline transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015193 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1902047 |
polyamine transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015203 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006865 |
amino acid transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0022857 |
transmembrane transporter activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055085 |
transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006865 |
amino acid transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Sáenz, DA et al. (2014) L-Phenylalanine Transport in Saccharomyces cerevisiae: Participation of GAP1, BAP2, and AGP1. J Amino Acids 2014 283962 PubMed GONUTS page
- ↑ Yofe, I et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat. Methods 13 371-378 PubMed GONUTS page
- ↑ Saliba, E et al. (2018) The yeast H-ATPase Pma1 promotes Rag/Gtr-dependent TORC1 activation in response to H-coupled nutrient uptake. Elife 7 PubMed GONUTS page
- ↑ Malkus, P et al. (2002) Concentrative sorting of secretory cargo proteins into COPII-coated vesicles. J. Cell Biol. 159 915-21 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Uemura, T et al. (2005) Uptake of putrescine and spermidine by Gap1p on the plasma membrane in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 328 1028-33 PubMed GONUTS page
- ↑ Andréasson, C et al. (2004) Four permeases import proline and the toxic proline analogue azetidine-2-carboxylate into yeast. Yeast 21 193-9 PubMed GONUTS page
- ↑ 7.0 7.1 Grenson, M & Acheroy, B (1982) Mutations affecting the activity and the regulation of the general amino-acid permease of Saccharomyces cerevisiae. Localisation of the cis-acting dominant pgr regulatory mutation in the structural gene of this permease. Mol. Gen. Genet. 188 261-5 PubMed GONUTS page
- ↑ Roberg, KJ et al. (1997) Physiological regulation of membrane protein sorting late in the secretory pathway of Saccharomyces cerevisiae. J. Cell Biol. 137 1469-82 PubMed GONUTS page
- ↑ Kota, J & Ljungdahl, PO (2005) Specialized membrane-localized chaperones prevent aggregation of polytopic proteins in the ER. J. Cell Biol. 168 79-88 PubMed GONUTS page
- ↑ Nikko, E et al. (2003) Permease recycling and ubiquitination status reveal a particular role for Bro1 in the multivesicular body pathway. J. Biol. Chem. 278 50732-43 PubMed GONUTS page
- ↑ 11.0 11.1 Scott, PM et al. (2004) GGA proteins bind ubiquitin to facilitate sorting at the trans-Golgi network. Nat. Cell Biol. 6 252-9 PubMed GONUTS page
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