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YEAST:FUN30
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | FUN30 | |
| Protein Name(s) | ATP-dependent helicase FUN30 | |
| External Links | ||
| UniProt | P31380 | |
| EMBL | L05146 BK006935 | |
| PIR | S22266 | |
| RefSeq | NP_009383.1 | |
| ProteinModelPortal | P31380 | |
| BioGrid | 31747 | |
| DIP | DIP-2541N | |
| IntAct | P31380 | |
| MINT | MINT-425278 | |
| STRING | 4932.YAL019W | |
| MaxQB | P31380 | |
| PaxDb | P31380 | |
| PeptideAtlas | P31380 | |
| EnsemblFungi | [example_ID YAL019W] | |
| GeneID | 851214 | |
| KEGG | sce:YAL019W | |
| CYGD | YAL019w | |
| SGD | S000000017 | |
| eggNOG | COG0553 | |
| GeneTree | ENSGT00630000089890 | |
| HOGENOM | HOG000195581 | |
| InParanoid | P31380 | |
| KO | K14439 | |
| OMA | GINLVCA | |
| OrthoDB | EOG7WDNB3 | |
| BioCyc | YEAST:G3O-28831-MONOMER | |
| NextBio | 968097 | |
| Proteomes | UP000002311 | |
| Genevestigator | P31380 | |
| GO | GO:0000775 GO:0031934 GO:0005634 GO:0005524 GO:0003682 GO:0003677 GO:0008094 GO:0004386 GO:0006200 GO:0043044 GO:0000183 GO:0030466 GO:0006348 GO:0000729 GO:0070869 GO:0070870 | |
| Gene3D | 3.40.50.300 | |
| InterPro | IPR014001 IPR001650 IPR027417 IPR000330 | |
| Pfam | PF00271 PF00176 | |
| SMART | SM00487 SM00490 | |
| SUPFAM | SSF52540 | |
| PROSITE | PS51192 PS51194 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042766 |
nucleosome mobilization |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008094 |
DNA-dependent ATPase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006338 |
chromatin remodeling |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016584 |
nucleosome positioning |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070870 |
heterochromatin maintenance involved in chromatin silencing |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000000449 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0070870 |
heterochromatin maintenance involved in chromatin silencing |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070869 |
heterochromatin assembly involved in chromatin silencing |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043044 |
ATP-dependent chromatin remodeling |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031934 |
mating-type region heterochromatin |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030466 |
chromatin silencing at silent mating-type cassette |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008094 |
DNA-dependent ATPase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008094 |
DNA-dependent ATPase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006348 |
chromatin silencing at telomere |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003682 |
chromatin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000775 |
chromosome, centromeric region |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000729 |
DNA double-strand break processing |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000729 |
DNA double-strand break processing |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000183 |
chromatin silencing at rDNA |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000781 |
chromosome, telomeric region |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0006348 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004386 |
helicase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006325 |
chromatin organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005694 |
chromosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Reinders, J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J. Proteome Res. 5 1543-54 PubMed GONUTS page
- ↑ Sickmann, A et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc. Natl. Acad. Sci. U.S.A. 100 13207-12 PubMed GONUTS page
- ↑ Huh, WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425 686-91 PubMed GONUTS page
- ↑ Tkach, JM et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat. Cell Biol. 14 966-76 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 Byeon, B et al. (2013) The ATP-dependent chromatin remodeling enzyme Fun30 represses transcription by sliding promoter-proximal nucleosomes. J. Biol. Chem. 288 23182-93 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Yu, Q et al. (2011) Roles of chromatin remodeling factors in the formation and maintenance of heterochromatin structure. J. Biol. Chem. 286 14659-69 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 7.4 Awad, S et al. (2010) The Snf2 homolog Fun30 acts as a homodimeric ATP-dependent chromatin-remodeling enzyme. J. Biol. Chem. 285 9477-84 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 8.4 Neves-Costa, A et al. (2009) The SNF2-family member Fun30 promotes gene silencing in heterochromatic loci. PLoS ONE 4 e8111 PubMed GONUTS page
- ↑ Durand-Dubief, M et al. (2012) SWI/SNF-like chromatin remodeling factor Fun30 supports point centromere function in S. cerevisiae. PLoS Genet. 8 e1002974 PubMed GONUTS page
- ↑ Chen, X et al. (2012) The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends. Nature 489 576-80 PubMed GONUTS page
- ↑ Costelloe, T et al. (2012) The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection. Nature 489 581-4 PubMed GONUTS page
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