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YEAST:ELP3

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) ELP3 (synonyms: HPA1, TOT3)
Protein Name(s) Elongator complex protein 3

Gamma-toxin target 3

External Links
UniProt Q02908
EMBL U43281
BK006949
PIR S61980
RefSeq NP_015239.1
ProteinModelPortal Q02908
SMR Q02908
BioGrid 36095
DIP DIP-2385N
IntAct Q02908
MINT Q02908
STRING 4932.YPL086C
iPTMnet Q02908
MaxQB Q02908
PaxDb Q02908
PRIDE Q02908
EnsemblFungi YPL086C
GeneID 856019
KEGG sce:YPL086C
EuPathDB FungiDB:YPL086C
SGD S000006007
GeneTree ENSGT00390000013141
HOGENOM HOG000227514
InParanoid Q02908
KO K07739
OMA SYTGKEP
OrthoDB EOG092C1F4W
BioCyc YEAST:G3O-33992-MONOMER
PRO PR:Q02908
Proteomes UP000002311
GO GO:0005737
GO:0005829
GO:0033588
GO:0005719
GO:0005654
GO:0005634
GO:0004402
GO:0051536
GO:0046872
GO:0009294
GO:0015031
GO:0010928
GO:2000025
GO:0006357
GO:0006351
GO:0002098
Gene3D 3.80.30.20
InterPro IPR016181
IPR034687
IPR006638
IPR000182
IPR032432
IPR007197
IPR023404
PANTHER PTHR11135:SF0
Pfam PF00583
PF04055
PF16199
PIRSF PIRSF005669
SFLD SFLDF00344
SMART SM00729
SUPFAM SSF55729
TIGRFAMs TIGR01211
PROSITE PS51186

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0033588

Elongator holoenzyme complex

PMID:11689709[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

PMID:11689709[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:12139626[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:12139626[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004402

histone acetyltransferase activity

PMID:10445034[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004402

histone acetyltransferase activity

PMID:10445034[3]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q03330

F

Seeded From UniProt

complete

involved_in

GO:0002098

tRNA wobble uridine modification

PMID:18755837[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0033588

Elongator holoenzyme complex

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000123915
SGD:S000006007
TAIR:locus:2177477
UniProtKB:Q9H9T3

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0031604
PANTHER:PTN000123913
SGD:S000006007
UniProtKB:Q9H9T3

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000123915
SGD:S000006007
TAIR:locus:2177477

C

Seeded From UniProt

complete

involved_in

GO:0002926

tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000123913
PomBase:SPAC29A4.20

P

Seeded From UniProt

complete

involved_in

GO:0016573

histone acetylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004402

P

Seeded From UniProt

complete

involved_in

GO:0016573

histone acetylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004402

P

Seeded From UniProt

complete

involved_in

GO:0016573

histone acetylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004402

P

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006638
InterPro:IPR007197

F

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006638
InterPro:IPR007197

F

Seeded From UniProt

complete

enables

GO:0004402

histone acetyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.3.1.48

F

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-NUL-4549261

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016746

transferase activity, transferring acyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0012

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0411

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0006325

chromatin organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0156

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Krogan, NJ & Greenblatt, JF (2001) Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 21 8203-12 PubMed GONUTS page
  2. 2.0 2.1 Fichtner, L et al. (2002) Protein interactions within Saccharomyces cerevisiae Elongator, a complex essential for Kluyveromyces lactis zymocicity. Mol. Microbiol. 45 817-26 PubMed GONUTS page
  3. 3.0 3.1 Wittschieben, BO et al. (1999) A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme. Mol. Cell 4 123-8 PubMed GONUTS page
  4. Huang, B et al. (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14 2183-94 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page