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YEAST:DUG2
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | DUG2 | |
| Protein Name(s) | Probable di- and tripeptidase DUG2
Deficient in utilization of glutathione protein 2 GSH degradosomal complex subunit DUG2 | |
| External Links | ||
| UniProt | P38149 | |
| EMBL | X76053 Z36150 BK006936 | |
| PIR | S44543 | |
| RefSeq | NP_009840.3 | |
| ProteinModelPortal | P38149 | |
| SMR | P38149 | |
| BioGrid | 32975 | |
| DIP | DIP-1612N | |
| IntAct | P38149 | |
| MINT | MINT-399156 | |
| STRING | 4932.YBR281C | |
| MaxQB | P38149 | |
| PaxDb | P38149 | |
| PeptideAtlas | P38149 | |
| EnsemblFungi | [example_ID YBR281C] | |
| GeneID | 852584 | |
| KEGG | sce:YBR281C | |
| CYGD | YBR281c | |
| SGD | S000000485 | |
| eggNOG | COG0624 | |
| HOGENOM | HOG000183136 | |
| InParanoid | P38149 | |
| KO | K14262 | |
| OMA | PAAHLPC | |
| OrthoDB | EOG7NW6JF | |
| BioCyc | YEAST:G3O-29201-MONOMER | |
| NextBio | 971733 | |
| Proteomes | UP000002311 | |
| Genevestigator | P38149 | |
| GO | GO:0005737 GO:0005634 GO:0016805 GO:0046872 GO:0008237 GO:0008242 GO:0008233 GO:0006751 | |
| Gene3D | 2.130.10.10 3.30.70.360 | |
| InterPro | IPR020472 IPR017149 IPR002933 IPR011650 IPR015943 IPR001680 IPR019775 IPR017986 | |
| Pfam | PF07687 PF01546 PF00400 | |
| PIRSF | PIRSF037237 | |
| PRINTS | PR00320 | |
| SMART | SM00320 | |
| SUPFAM | SSF50978 SSF55031 | |
| PROSITE | PS00678 PS50082 PS50294 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0034399 |
nuclear periphery |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
exists_during:(GO:0006974) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0061672 |
glutathione hydrolase complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008242 |
omega peptidase activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000004290 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000004294 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006751 |
glutathione catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006751 |
glutathione catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006751 |
glutathione catabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
contributes_to |
GO:0036374 |
glutathione hydrolase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006751 |
glutathione catabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016805 |
dipeptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008237 |
metallopeptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Huh, WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425 686-91 PubMed GONUTS page
- ↑ Gallina, I et al. (2015) Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control. Nat Commun 6 6533 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Kaur, H et al. (2012) Glutathione degradation by the alternative pathway (DUG pathway) in Saccharomyces cerevisiae is initiated by (Dug2p-Dug3p)2 complex, a novel glutamine amidotransferase (GATase) enzyme acting on glutathione. J. Biol. Chem. 287 8920-31 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Ganguli, D et al. (2007) The alternative pathway of glutathione degradation is mediated by a novel protein complex involving three new genes in Saccharomyces cerevisiae. Genetics 175 1137-51 PubMed GONUTS page
