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YEAST:BAP2

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) BAP2
Protein Name(s) Leu/Val/Ile amino-acid permease

Branched-chain amino-acid permease 2

External Links
UniProt P38084
EMBL Z35937
BK006936
PIR S45930
RefSeq NP_009624.4
ProteinModelPortal P38084
SMR P38084
BioGrid 32771
DIP DIP-4910N
IntAct P38084
MINT MINT-516615
STRING 4932.YBR068C
TCDB 2.A.3.10.6
MaxQB P38084
PaxDb P38084
PeptideAtlas P38084
EnsemblFungi [example_ID YBR068C]
GeneID 852360
KEGG sce:YBR068C
CYGD YBR068c
SGD S000000272
eggNOG COG0833
GeneTree ENSGT00510000049744
HOGENOM HOG000261848
InParanoid P38084
KO K16261
OMA DFHRRIY
OrthoDB EOG74J9HZ
BioCyc YEAST:G3O-29037-MONOMER
NextBio 971125
Proteomes UP000002311
Genevestigator P38084
GO GO:0016021
GO:0005886
GO:0015171
GO:0006865
GO:0055085
InterPro IPR004841
IPR002293
IPR004762
IPR004840
PANTHER PTHR11785
Pfam PF00324
PIRSF PIRSF006060
TIGRFAMs TIGR00913
PROSITE PS00218

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0015192

L-phenylalanine transmembrane transporter activity

PMID:24701347[1]

ECO:0000315

F

Figure 1 shows BAP2 to be the major permease responsible for high affinity phenylalanine transport

complete
CACAO 9973

GO:1990122

leucine import into cell

PMID:24699373[2]

ECO:0000315

P

Figure 1A shows the OD concentrations of leucine from a cell for both wild types strains and for mutant strains. The wild type, with a BAP2 gene, has the highest OD of leucine and the mutants have decreased ODs.

complete
CACAO 10100

part_of

GO:0005783

endoplasmic reticulum

PMID:26928762[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0015192

L-phenylalanine transmembrane transporter activity

PMID:24701347[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0098713

leucine import across plasma membrane

PMID:24699373[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

PMID:10654085[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0015171

amino acid transmembrane transporter activity

PMID:10654085[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006865

amino acid transport

PMID:10654085[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:10654085[4]

ECO:0000250

sequence similarity evidence used in manual assertion

C

Seeded From UniProt

Missing: with/from

involved_in

GO:0015823

phenylalanine transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015192

P

Seeded From UniProt

complete

involved_in

GO:0006865

amino acid transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004762
InterPro:IPR004840

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002293
InterPro:IPR004841

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004762
InterPro:IPR004840

C

Seeded From UniProt

complete

enables

GO:0022857

transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002293

F

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002293
InterPro:IPR004840
InterPro:IPR004841

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0006865

amino acid transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0029

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Sáenz, DA et al. (2014) L-Phenylalanine Transport in Saccharomyces cerevisiae: Participation of GAP1, BAP2, and AGP1. J Amino Acids 2014 283962 PubMed GONUTS page
  2. 2.0 2.1 Usami, Y et al. (2014) Functional mapping and implications of substrate specificity of the yeast high-affinity leucine permease Bap2. Biochim. Biophys. Acta 1838 1719-29 PubMed GONUTS page
  3. Yofe, I et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat. Methods 13 371-378 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Regenberg, B et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr. Genet. 36 317-28 PubMed GONUTS page