XENTR:F6WBH7

Species (Taxon ID)	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis). (8364)
Gene Name(s)	iqgap1 (ECO:0000313 with Ensembl:ENSXETP00000002788)
Protein Name(s)	Uncharacterized protein (ECO:0000313 with Ensembl:ENSXETP00000002788)
External Links
UniProt	F6WBH7
EMBL	AAMC01010614 AAMC01010615 AAMC01010616 AAMC01010617 AAMC01010618 AAMC01010619 AAMC01010620
Ensembl	ENSXETT00000002788
Xenbase	XB-GENE-492063
GeneTree	ENSGT00600000084379
InParanoid	F6WBH7
OMA	QDILYQA
OrthoDB	EOG7FNC6M
TreeFam	TF313078
Reactome	REACT_220273
Proteomes	UP000008143
Bgee	F6WBH7
ExpressionAtlas	F6WBH7
GO	GO:0005622 GO:0005099 GO:0007264
Gene3D	1.10.418.10 1.10.506.10 4.10.270.10
InterPro	IPR001715 IPR000048 IPR027401 IPR027417 IPR000593 IPR023152 IPR001936 IPR008936 IPR001202
Pfam	PF00307 PF00612 PF00616 PF03836
SMART	SM00033 SM00015 SM00323
SUPFAM	SSF47576 SSF48350 SSF52540
PROSITE	PS50021 PS50096 PS00509 PS50018 PS01159 PS50020

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0006606	protein import into nucleus	PMID:23577172	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
	GO:0060070	canonical Wnt receptor signaling pathway	PMID:23577172	ECO:0000315			P		The results presented in Fig. 4 (A-H) suggest “that xIQGAP1 is necessary for Wnt-related early embryogenesis” and functions as an intermediate molecule in the pathway. Additionally, the results in Fig 5 also support that binding between xDVL2 and xIQGAP1 plays an important role in canonical Wnt signaling.	complete CACAO 7906
part_of	GO:0005623	cell	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0006606	C		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008936	P		Seeded From UniProt	complete
involved_in	GO:0043087	regulation of GTPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001936 InterPro:IPR023152	P		Seeded From UniProt	complete
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References

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