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XENLA:SHRM3

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Species (Taxon ID) Xenopus laevis (African clawed frog). (8355)
Gene Name(s) shroom3 (synonyms: shrm)
Protein Name(s) Protein Shroom3

Shroom-like protein

External Links
UniProt Q27IV2
EMBL DQ398586
RefSeq NP_001089158.1
UniGene Xl.12192
PRIDE Q27IV2
GeneID 734194
KEGG xla:734194
CTD 57619
Xenbase XB-GENE-490228
KO K18625
GO GO:0005912
GO:0016324
GO:0005737
GO:0005856
GO:0005874
GO:0003779
GO:0045176
GO:0000902
GO:0043482
GO:0007389
GO:0008360
InterPro IPR014800
IPR014799
IPR027685
PANTHER PTHR15012
Pfam PF08688
PF08687
PROSITE PS51306
PS51307

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0048546

digestive tract morphogenesis

PMID:20332151[1]

ECO:0000314

P

Fig 1 depicts how Shroom3 is is essential for morphogenesis of the developing gut

complete
CACAO 5046

GO:0003382

epithelial cell morphogenesis

PMID:20332151[1]

ECO:0000314

P

Fig 6D depicts Shroom3 expression in the epidermis

complete
CACAO 5047

involved_in

GO:0045176

apical protein localization

PMID:16987870[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043482

cellular pigment accumulation

PMID:16987870[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9QXN0

C

Seeded From UniProt

complete

involved_in

GO:0007389

pattern specification process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9QXN0

P

Seeded From UniProt

complete

part_of

GO:0005912

adherens junction

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9QXN0

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9QXN0

C

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9QXN0

F

Seeded From UniProt

complete

involved_in

GO:0000902

cell morphogenesis

PMID:16987870[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000902

cell morphogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030494

P

Seeded From UniProt

complete

involved_in

GO:0001843

neural tube closure

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030494

P

Seeded From UniProt

complete

involved_in

GO:0002064

epithelial cell development

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030494

P

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030494

F

Seeded From UniProt

complete

enables

GO:0051015

actin filament binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014800
InterPro:IPR027685

F

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0009

F

Seeded From UniProt

complete

part_of

GO:0005874

microtubule

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0493

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

involved_in

GO:0008360

regulation of cell shape

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0133

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0005912

adherens junction

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0009

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Chung, MI et al. (2010) Direct activation of Shroom3 transcription by Pitx proteins drives epithelial morphogenesis in the developing gut. Development 137 1339-49 PubMed GONUTS page
  2. 2.0 2.1 2.2 Fairbank, PD et al. (2006) Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium. Development 133 4109-18 PubMed GONUTS page