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XENLA:OTX2A

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Species (Taxon ID) Xenopus laevis (African clawed frog). (8355)
Gene Name(s) otx2-a
Protein Name(s) Homeobox protein OTX2-A

xOTX2-A Orthodenticle 2-A Orthodenticle-A-like protein A

External Links
UniProt Q91813
EMBL Z46972
BC077357
L26509
PIR I51620
RefSeq NP_001084160.1
UniGene Xl.3004
ProteinModelPortal Q91813
SMR Q91813
GeneID 399342
KEGG xla:399342
CTD 399342
Xenbase XB-GENE-6254039
HOVERGEN HBG004028
GO GO:0005634
GO:0043565
GO:0003700
GO:0007275
GO:0045893
Gene3D 1.10.10.60
InterPro IPR017970
IPR001356
IPR009057
IPR003022
IPR003025
IPR013851
Pfam PF00046
PF03529
PRINTS PR01257
PR01255
SMART SM00389
SUPFAM SSF46689
PROSITE PS00027
PS50071

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:12710967[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:12710967[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:12710967[1]

ECO:0000305

curator inference used in manual assertion

GO:0043565

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001356
InterPro:IPR003022
InterPro:IPR003025
InterPro:IPR009057

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003022
InterPro:IPR003025
InterPro:IPR013851

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003022
InterPro:IPR003025
InterPro:IPR013851

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017970

P

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003022
InterPro:IPR003025
InterPro:IPR013851

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017970

F

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238
UniProtKB-KW:KW-0371

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Yamamoto, S et al. (2003) Molecular link in the sequential induction of the Spemann organizer: direct activation of the cerberus gene by Xlim-1, Xotx2, Mix.1, and Siamois, immediately downstream from Nodal and Wnt signaling. Dev. Biol. 257 190-204 PubMed GONUTS page