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XENLA:O57537

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Species (Taxon ID) Xenopus laevis (African clawed frog). (8355)
Gene Name(s) pcdh7 (ECO:0000313 with Xenbase:XB-GENE-1007361) (synonyms: NFPC (ECO:0000313 with EMBL:AAC41270.1))
Protein Name(s) NF-protocadherin (ECO:0000313 with EMBL:AAC41270.1)
External Links
UniProt O57537
EMBL AF043643
RefSeq NP_001165662.1
UniGene Xl.315
ProteinModelPortal O57537
SMR O57537
GeneID 100337580
KEGG xla:100337580
CTD 5099
Xenbase XB-GENE-1007361
HOVERGEN HBG053523
KO K16498
GO GO:0016021
GO:0005886
GO:0005509
GO:0007156
Gene3D 2.60.40.60
InterPro IPR002126
IPR015919
IPR020894
IPR013164
IPR013585
Pfam PF00028
PF08266
PF08374
PRINTS PR00205
SMART SM00112
SUPFAM SSF49313
PROSITE PS00232
PS50268

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0007155

cell adhesion

PMID:9512415[1]

ECO:0000314

P

Cell mixing assays in Figures 5-7 compare NFPC to known adhesion molecules, supporting the assumption this is an adhesion molecule.

complete
CACAO 7208

GO:0007398

ectoderm development

PMID:9512415[1]

ECO:0000314

P

Figures 3 and 4 show expression in the ectoderm during development. Its expression is similar to other ectodermal markers.

complete
CACAO 7360

involved_in

GO:0007398

ectoderm development

PMID:9512415[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

PMID:9512415[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002126
InterPro:IPR015919

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020894

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020894

P

Seeded From UniProt

complete

involved_in

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002126

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002126
InterPro:IPR015919

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Bradley, RS et al. (1998) NF-protocadherin, a novel member of the cadherin superfamily, is required for Xenopus ectodermal differentiation. Curr. Biol. 8 325-34 PubMed GONUTS page