GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:9512415
| Citation |
Bradley, RS, Espeseth, A and Kintner, C (1998) NF-protocadherin, a novel member of the cadherin superfamily, is required for Xenopus ectodermal differentiation. Curr. Biol. 8:325-34 |
|---|---|
| Abstract |
The assembly of complex tissues during embryonic development is thought to depend on differential cell adhesion, mediated in part by the cadherin family of cell-adhesion molecules. The protocadherins are a new subfamily of cadherins; their extracellular domains comprise cadherin-like repeats but their intracellular domains differ significantly from those of classical cadherins. Little is known about the ability of protocadherins to mediate the adhesion of embryonic cells, or whether they play a role in the formation of embryonic tissues. |
| Links | |
| Keywords |
Animals; Blister/chemically induced; Cadherins/chemistry; Cadherins/isolation & purification; Cadherins/physiology; Cell Adhesion Molecules/physiology; DNA, Complementary; Ectoderm/metabolism; Gene Expression Regulation, Developmental/physiology; Immunochemistry; In Situ Hybridization; RNA; Sequence Alignment; Xenopus/embryology; Xenopus Proteins |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0007155: cell adhesion |
ECO:0000314: direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0007155: cell adhesion |
ECO:0000314: |
P |
Cell mixing assays in Figures 5-7 compare NFPC to known adhesion molecules, supporting the assumption this is an adhesion molecule. |
complete | ||||
| GO:0007398: ectoderm development |
ECO:0000314: |
P |
Figures 3 and 4 show expression in the ectoderm during development. Its expression is similar to other ectodermal markers. |
complete | ||||
|
involved_in |
GO:0007398: ectoderm development |
ECO:0000314: direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
See also
References
See Help:References for how to manage references in GONUTS.
