XENLA:NU153

Species (Taxon ID)	Xenopus laevis (African clawed frog). (8355)
Gene Name(s)	nup153
Protein Name(s)	Nuclear pore complex protein Nup153 153 kDa nucleoporin Nucleoporin Nup153
External Links
UniProt	Q640Z6
EMBL	BC082443
RefSeq	NP_001082284.1
UniGene	Xl.46998 Xl.49808
ProteinModelPortal	Q640Z6
BioGrid	99706
GeneID	398374
KEGG	xla:398374
CTD	398374
Xenbase	XB-GENE-6251581
HOVERGEN	HBG052679
KO	K14296
GO	GO:0031965 GO:0005643 GO:0003677 GO:0008270 GO:0051028 GO:0015031
Gene3D	4.10.1060.10
InterPro	IPR026054 IPR013913 IPR001876
PANTHER	PTHR23193
Pfam	PF08604 PF00641
SMART	SM00547
SUPFAM	SSF90209
PROSITE	PS01358 PS50199

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0031965	nuclear membrane	PMID:26051542	ECO:0000314			C		The N-terminal fragment of Xenopus Nup153 fused to EGFP, when ectopically expressed in HeLa cells, localized to the NE, presumably the inner nuclear membrane ( Figures 1F and S1C).	complete CACAO 12838
	GO:0051292	nuclear pore complex assembly	PMID:26051542	ECO:0000315			P		Organism: Xenopus Laevis Protein: Nup153/Nup153 Figure 3B-D: " Addition of 2 μM importin β, which blocks interphasic NPC assembly (D’Angelo et al., 2006), to nuclei formed under control conditions resulted in a reduction in the number of NPCs per nucleus by approximately 60% when added 50 min after starting the reaction (Figure 3B)."	complete CACAO 12839
	GO:0005789	endoplasmic reticulum membrane	PMID:26051542	ECO:0000315			C		Orgasnism: Xenopus Laevis Protein: Nup153//Nup153 Figure 6 " Membranes were incubated with control or Nup153-depleted cytosol, re-isolated, and analyzed by western blotting (Figures 6A and 6B ). ... Nup153 depletion severely reduced the quantity of soluble nucleoporins re-isolated with membranes."	complete CACAO 12846
involved_in	GO:0006913	nucleocytoplasmic transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0017056	P		Seeded From UniProt	complete
enables	GO:0017056	structural constituent of nuclear pore	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR037625	F		Seeded From UniProt	complete
involved_in	GO:0051028	mRNA transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0509	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539	C		Seeded From UniProt	complete
part_of	GO:0005643	nuclear pore	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0906 UniProtKB-SubCell:SL-0185	C		Seeded From UniProt	complete
involved_in	GO:0015031	protein transport	GO_REF:0000037 GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0653 UniProtKB-KW:KW-0811	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
part_of	GO:0031965	nuclear membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0182	C		Seeded From UniProt	complete
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References

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