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XENLA:MEI3A

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Species (Taxon ID) Xenopus laevis (African clawed frog). (8355)
Gene Name(s) meis3-a (synonyms: meis3 (ECO:0000312 with EMBL:AAH84920.1))
Protein Name(s) Homeobox protein meis3-A (ECO:0000250 with UniProtKB:Q99687, ECO:0000312 with EMBL:AAH84920.1)

XMeis3 (ECO:0000250 with UniProtKB:Q99687, ECO:0000303 with PMID:10096059[1], ECO:0000303 with PMID:11566848[2])

External Links
UniProt Q5U4X3
EMBL AF072895
BC084920
RefSeq NP_001081866.1
UniGene Xl.452
ProteinModelPortal Q5U4X3
SMR Q5U4X3
GeneID 398093
KEGG xla:398093
CTD 398093
Xenbase XB-GENE-6252025
HOVERGEN HBG055193
KO K16671
GO GO:0005737
GO:0005634
GO:0003677
GO:0009952
GO:0030154
GO:0007417
GO:0030902
GO:0043410
GO:0045944
GO:0045893
GO:0006351
Gene3D 1.10.10.60
InterPro IPR001356
IPR008422
IPR009057
Pfam PF05920
SMART SM00389
SUPFAM SSF46689
PROSITE PS50071

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:11566848[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:11566847[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:11566848[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043410

positive regulation of MAPK cascade

PMID:14660437[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030902

hindbrain development

PMID:15196951[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030902

hindbrain development

PMID:14660437[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030902

hindbrain development

PMID:11566848[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009952

anterior/posterior pattern specification

PMID:10096059[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007417

central nervous system development

PMID:10096059[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q90ZE3

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q90ZE3

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q90ZE3

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001356
InterPro:IPR008422
InterPro:IPR009057

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008422

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238
UniProtKB-KW:KW-0371

F

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Salzberg, A et al. (1999) A Meis family protein caudalizes neural cell fates in Xenopus. Mech. Dev. 80 3-13 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Dibner, C et al. (2001) XMeis3 protein activity is required for proper hindbrain patterning in Xenopus laevis embryos. Development 128 3415-26 PubMed GONUTS page
  3. Inbal, A et al. (2001) Genetic evidence for the transcriptional-activating function of Homothorax during adult fly development. Development 128 3405-13 PubMed GONUTS page
  4. 4.0 4.1 Aamar, E & Frank, D (2004) Xenopus Meis3 protein forms a hindbrain-inducing center by activating FGF/MAP kinase and PCP pathways. Development 131 153-63 PubMed GONUTS page
  5. Dibner, C et al. (2004) The Meis3 protein and retinoid signaling interact to pattern the Xenopus hindbrain. Dev. Biol. 271 75-86 PubMed GONUTS page