VIBCH:Q9KLE3

Species (Taxon ID)	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961). (243277)
Gene Name(s)	No Information Provided.
Protein Name(s)	Serine protease, putative (ECO:0000313 with EMBL:AAF96701.1)
External Links
UniProt	Q9KLE3
EMBL	AE003853
PIR	B82415
RefSeq	NP_233189.1
ProteinModelPortal	Q9KLE3
STRING	243277.VCA0803
MEROPS	S01.515
DNASU	2612776
EnsemblBacteria	AAF96701
GeneID	2612776
KEGG	vch:VCA0803
PATRIC	20086154
OMA	AHCVDYQ
OrthoDB	EOG6VMTQS
BioCyc	VCHO:VCA0803-MONOMER
Proteomes	UP000000584
GO	GO:0008233 GO:0004252 GO:0006508
InterPro	IPR001254 IPR018114 IPR001314 IPR009003
Pfam	PF00089
PRINTS	PR00722
SMART	SM00020
SUPFAM	SSF50494
PROSITE	PS50240 PS00134 PS00135

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0051605	protein maturation by peptide bond cleavage	PMID:21385872	ECO:0000315			P		Fig 5 A-B VesA is responsible for the majority of the proteolytic cleavage of the Cholerae Toxin A subunit. In absence of VesA up to 80% of the Cholerae Toxin remained unprocessed	complete
	GO:0008236	serine-type peptidase activity	PMID:21385872	ECO:0000315			F		Figure 2B shows that VesA participates in hydrolysis of peptide bonds-i.e. peptidase activity.In addition overexpression of VesA resulted in an increase in enzymatic activity (Fig 3A). Figure 3A show that the serine protease inhibitor AEBSF and the serine/cysteine protease inhibitor significantly inhibited the VesA protein.	complete
enables	GO:0008233	peptidase activity	PMID:10952301	ECO:0000250	sequence similarity evidence used in manual assertion		F		Seeded From UniProt	Missing: with/from
involved_in	GO:0006508	proteolysis	PMID:10952301	ECO:0000250	sequence similarity evidence used in manual assertion		P		Seeded From UniProt	Missing: with/from
enables	GO:0004252	serine-type endopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001254 InterPro:IPR001314 InterPro:IPR018114	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001254 InterPro:IPR001314 InterPro:IPR018114	P		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
enables	GO:0008236	serine-type peptidase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0720	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F		Seeded From UniProt	complete
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References

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