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User:Navpreet

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
requireschangesYEAST:CSI12011-12-11 12:24:20 CSTGO:0000338 protein deneddylation (P)PMID:12186635ECO:0000314 direct assay evidence used in manual assertion

Disruption of genes encoding Rri1p/Csn5p-associated proteins causes accumulation of Rub1p-modified Cdc53p.. figure 1

similar to fission yeast csn mutants, budding yeast Δcsn strains have a biochemical defect in the removal of Rub1p from Cdc53p, suggesting that the Rri1p/Csn5p, Csn9p, Rri2p/Csn10p, Pci8p/Csn11p, and Csi1p complex represents a budding yeast equivalent of the CSN complex described in fission yeast, plants, and human cells. figure2

challenge
requireschangesYEAST:BPH12011-12-05 19:57:01 CSTGO:0000300 peripheral to membrane of membrane fraction (C)PMID:15296494ECO:0000314 direct assay evidence used in manual assertion

The δbph1 strain showed an impaired growth on defined synthetic media containing potassium acetate buffered below pH 4.25, increased sensitivity to calcofluor white, and increased agglutination in response to low pH, results in the formation of enlarged lysosomes, defective

immune cell function. figure 1 and 2

challenge
requireschangesMOUSE:HIPK12011-12-06 21:13:28 CSTGO:0061072 iris morphogenesis (P)PMID:9748262ECO:0000315 mutant phenotype evidence used in manual assertion

figure 2 , figure 3

challenge

acceptable:0
unacceptable:0
requires_changes:3
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Annotations challenged by Navpreet

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