User:Gilbe205

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	BOMMO:H9JTG9	2014-04-06 12:13:51 CDT	GO:0004033 aldo-keto reductase (NADP) activity (F)	PMID:24012638	ECO:0000266 sequence orthology evidence used in manual assertion	Figure 2 shows sequence and structural homology to other defined aldo-keto reductases, notably human aldo-keto reductase AKR1C2.	challenge
unacceptable	ECOLI:GLGB	2014-04-06 12:32:45 CDT	GO:0003844 1,4-alpha-glucan branching enzyme activity (F)	PMID:12196524	ECO:0000315 mutant phenotype evidence used in manual assertion	Table 5 shows sequence point mutations, deletions or truncations that result in glycogen storage disease type IV, caused by lethal or retarded function of glycogen branching enzyme.	challenge
unacceptable	ECOLI:GLGB	2014-04-06 12:57:04 CDT	GO:0004373 glycogen (starch) synthase activity (F)	PMID:19244233	ECO:0000266 sequence orthology evidence used in manual assertion	Table 2 presents the partial alignment of conserved residues between Escherichia coli glycogen synthase and other bacterial glycogen syntheses and plant starch syntheses.	challenge
acceptable	HUMAN:INO1	2014-04-06 14:23:22 CDT	GO:0004512 inositol-3-phosphate synthase activity (F)	PMID:23902760	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 8C shows the effect of point mutations on the activity of the inositol-3-phosphate synthase. The assay measured the inorganic phosphate liberated from glucose 6-phosphate which is dependent on the activity of the synthase enzyme.	challenge
unacceptable	ECOLI:OMPF	2014-04-06 15:45:02 CDT	GO:0015288 porin activity (F)	PMID:8702816	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3 shows the differing growth rate of wild-type and OmpF mutants when grown on maltotriose and maltooligosaccharides. The N-terminal mutations allow for growth on carbon sources larger than the normal exclusion limit.	challenge

acceptable:1
unacceptable:4
requires_changes:0
flagged:0

Annotations challenged by Gilbe205

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

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