User:Emuehlenkamp

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	DROME:TERA	2013-10-21 15:21:34 CDT	GO:0046907 intracellular transport (P)	PMID:23790629	ECO:0000255 match to sequence model evidence used in manual assertion	Table 1.Valosin-containing protein (VCP) homologue function categorized by DAVID and receiving the highest MASCOT score in anti-myc affinity purification and mass-spectrometry with the protein atlastin.	challenge
unacceptable	DROME:TERA	2013-11-04 13:57:33 CST	GO:0016485 protein processing (P)	PMID:23790629	ECO:0000317 genomic context evidence used in manual assertion	Fig. 1B. Proteins are identified through DAVID and again through DroPNet and constructed into a web through Cytoscape. Valosin-containing protein (VCP) homologue (TER94) is found in th protein processing section of the atlastin interactome web.	challenge
unacceptable	DROME:TERA	2013-11-04 14:12:55 CST	GO:0016485 protein processing (P)	PMID:23790629	ECO:0000316 genetic interaction evidence used in manual assertion	Fig. 2A. VCP is confirmed to interact with atlastin, known to function in protein processing, through co-immunoprecipitation.	challenge
requireschanges	DROME:TERA	2013-11-04 14:21:33 CST	GO:0007029 endoplasmic reticulum organization (P)	PMID:23790629	ECO:0000314 direct assay evidence used in manual assertion	Fig. 2B,C, and D all show atlastin and VCP in ER regions.	challenge
unacceptable	DROME:TERA	2013-11-04 14:26:54 CST	GO:0016485 protein processing (P)	PMID:23790629	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig. 4. VCP contributes to atlastin function. VCP expression directly influences atlastin expression as seen by large or rough eyes.	challenge
unacceptable	DROME:TERA	2013-11-04 14:33:17 CST	GO:0016485 protein processing (P)	PMID:23790629	ECO:0000314 direct assay evidence used in manual assertion	Fig. 5. Loss of VCP causes a suppression of the atlastin overexpression phenotype, rough or small eyes.	challenge
unacceptable	DROME:ATLAS	2013-11-04 18:33:48 CST	GO:0016050 vesicle organization (P)	PMID:19573020	ECO:0000314 direct assay evidence used in manual assertion	Fig. 2. Atlastin helps form vesicles with VSV-G and increases sensitivity to VSV-G.	challenge
unacceptable	DROME:ATLAS	2013-11-04 19:17:20 CST	GO:0071787 endoplasmic reticulum tubular network assembly (P)	PMID:19573020	ECO:0000314 direct assay evidence used in manual assertion	Fig. 3. Atlastin induces formation of tubules characteristic of the ER.	challenge
unacceptable	DROME:ATLAS	2013-11-04 19:32:46 CST		PMID:19573020	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig. 4. Vesicle formation from swollen tubules or ER.	challenge

acceptable:0
unacceptable:8
requires_changes:1
flagged:0

Annotations challenged by Emuehlenkamp

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
acceptable	Delwadia, Team People that mess up	AZOBR:NIFA	GO:2000144 - positive regulation of DNA-templated transcription initiation (P)	PMID:22267004	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 2

0 annotations fixed by Emuehlenkamp

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