User:Dbryant

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
acceptable	DICDI:Q54XI2	2018-04-12 09:36:34 CDT	GO:0006303 double-strand break repair via nonhomologous end joining (P)	PMID:21807880	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4, disruption of adprt1a cells had the lowest REMI index compared to disrupted Ku80 cells. Collective data show DSB-induced PARylation by Adprt1a promotes NHEJ over HR, indicating adprt1a has a role in promoting NHEJ repair pathway.	challenge
updatedbyinstructor	HUMAN:PNKP	2018-04-13 20:58:47 CDT	GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining (P)	PMID:12032095	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 6A&B, PNK depleted GM00558 extracts showed similar deficiency as RAD51-depleted extracts in promoting end joining of linear DNA molecules with 5’-OH termini.	challenge

acceptable:1
unacceptable:0
requires_changes:0
flagged:0

Annotations challenged by Dbryant

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

0 annotations fixed by Dbryant

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