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User:Albdan

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CACAO Spring 2014

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableBVDV:A0N0F02014-02-27 01:17:20 CSTGO:0043653 mitochondrial fragmentation involved in apoptotic process (P)PMID:24551175ECO:0000315 mutant phenotype evidence used in manual assertion

the Npro protein prevent fragmentation of mitochondria to inhibit apoptosis in response to cell stress in fig 2.

challenge
unacceptable?2014-02-27 18:32:03 CSTGO:0010628 positive regulation of gene expression (AMPK promotes DAF-16 activity, implies metabolic regulators in a positive feedback loop that accelerates the induction of DAF-16 target gene expression. from fig 5.)PMID:24516399IDA: Inferred from Direct Assay
challenge
unacceptableYEAST:IF2A2014-03-01 11:48:21 CSTGO:0039585 PKR signal transduction (P)PMID:24338483ECO:0000315 mutant phenotype evidence used in manual assertion

Protein kinase R (PKR) dimerization and activation loop autophosphorylation are mutually exclusive yet interdependent process. in fig 4.

challenge
acceptableBVDV:A0N0F02014-03-02 01:44:27 CSTGO:0043066 negative regulation of apoptotic process (P)PMID:24551175ECO:0000315 mutant phenotype evidence used in manual assertion

Inhibition of apoptosis by Npro correlates with degradation of IRF3 in fig 1.

challenge

acceptable:1
unacceptable:3
requires_changes:0
flagged:0

Annotations challenged by Albdan

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history

0 annotations fixed by Albdan

What do the icons mean in the status column?

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