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BVDV:A0N0F0
Contents
Species (Taxon ID) | Bovine viral diarrhea virus (BVDV) (Mucosal disease virus). (11099) | |
Gene Name(s) | Npro (ECO:0000313 with EMBL:ABK41017.1) | |
Protein Name(s) | N-terminal autoprotease (ECO:0000313 with EMBL:ABK41017.1) | |
External Links | ||
UniProt | A0N0F0 | |
EMBL | EF063119 | |
GO | GO:0008233 GO:0019082 | |
InterPro | IPR008751 | |
Pfam | PF05550 | |
ProDom | PD003091 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0043653 |
mitochondrial fragmentation involved in apoptotic process |
ECO:0000315 |
P |
the Npro protein prevent fragmentation of mitochondria to inhibit apoptosis in response to cell stress in fig 2. |
complete | |||||
GO:0043066 |
negative regulation of apoptotic process |
ECO:0000315 |
P |
Inhibition of apoptosis by Npro correlates with degradation of IRF3 in fig 1. |
complete | |||||
involved_in |
GO:0043066 |
negative regulation of apoptotic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016032 |
viral process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0019082 |
viral protein processing |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006508 |
proteolysis |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0008233 |
peptidase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Jefferson, M et al. (2014) The pestivirus N terminal protease N(pro) redistributes to mitochondria and peroxisomes suggesting new sites for regulation of IRF3 by N(pro.). PLoS ONE 9 e88838 PubMed GONUTS page