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TREDE:Q73JV3
Contents
| Species (Taxon ID) | Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222). (243275) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Uncharacterized protein (ECO:0000313 with EMBL:AAS13025.1) | |
| External Links | ||
| UniProt | Q73JV3 | |
| EMBL | AE017226 | |
| RefSeq | NP_973106.1 | |
| STRING | 243275.TDE2508 | |
| EnsemblBacteria | AAS13025 | |
| GeneID | 2739020 | |
| KEGG | tde:TDE2508 | |
| PATRIC | 20527088 | |
| BioCyc | TDEN243275:GJ7G-2552-MONOMER | |
| Proteomes | UP000008212 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:1900191 |
negative regulation of single-species biofilm formation |
ECO:0000315 |
P |
In Figure 7 the TDE2508-deficient Mutant and the wild type, T. denticola, were both incubated on a polystyrene plate for 2 days. After two days, the amount of biofilm formation and development of bacterial aggregates were measured. The mutant, which was TDE2508-deficient, had a substantial amount of biofilm formation and bacterial aggregates compared to the wild-type. The mutant's ability to produce more biofilm than the wild-type because of the deletion of TDE2508, supports the claim that TDE2508 is involved in the regulation of biofilm formation. |
complete | |||||
| GO:0030155 |
regulation of cell adhesion |
ECO:0000315 |
P |
In Figure 8 the TDE2508-deficient Mutant and the wild type, T. denticola, were both incubated with Ca9-22 epithelial cells for 1 hour. After one hour the Mutant showed significantly more adherence to human gingival epithelial cells at both high and low MOI. Since the figure shows the mutant, which is TDE2508-deficient, as having superior adherence compared to the wild-type, it is clear that the TDE2508 protein plays an important role in regulating cell adhesion. |
complete | |||||
|
involved_in |
GO:0030155 |
regulation of cell adhesion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1900191 |
negative regulation of single-species biofilm formation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
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