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TETTH:Q22XZ3

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Species (Taxon ID) Tetrahymena thermophila (strain SB210). (312017)
Gene Name(s) No Information Provided.
Protein Name(s) Alpha-tubulin N-acetyltransferase (ECO:0000255 with HAMAP-Rule:MF_03130)

Alpha-TAT (ECO:0000255 with HAMAP-Rule:MF_03130) TAT (ECO:0000255 with HAMAP-Rule:MF_03130) Acetyltransferase mec-17 homolog (ECO:0000255 with HAMAP-Rule:MF_03130)

External Links
UniProt Q22XZ3
EMBL GG662749
STRING 5911.XP_001010476
eggNOG NOG249793
InParanoid Q22XZ3
Proteomes UP000009168
GO GO:0019799
GO:0071929
GO:0070507
Gene3D 3.40.630.30
HAMAP MF_03130
InterPro IPR016181
IPR007965
PANTHER PTHR12327
Pfam PF05301
SUPFAM SSF55729
PROSITE PS51730

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0000062

acyl-CoA binding

PMID:20829795[1]

ECO:0000314

F

Figure 5a: the acetylation of alpha-tubulin in this assay was dependent on acetyl COA.

complete
CACAO 3597

GO:0019799

tubulin N-acetyltransferase activity

PMID:20829795[1]

ECO:0000315

F

Figure 1. Disrupted MEC17 showed a loss of acetyl-K40, as inferred from immunofluorescence with mAbs specific for acetyl-K40 on α-tubulin.

complete
CACAO 3596

involved_in

GO:0070507

regulation of microtubule cytoskeleton organization

PMID:20829795[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0019799

tubulin N-acetyltransferase activity

PMID:20829795[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005874

microtubule

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007965

C

Seeded From UniProt

complete

enables

GO:0019799

tubulin N-acetyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007965
InterPro:IPR038746

F

Seeded From UniProt

complete

involved_in

GO:0071929

alpha-tubulin acetylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007965

P

Seeded From UniProt

complete

enables

GO:0019799

tubulin N-acetyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.3.1.108

F

Seeded From UniProt

complete

enables

GO:0019799

tubulin N-acetyltransferase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000106988

F

Seeded From UniProt

complete

involved_in

GO:0070507

regulation of microtubule cytoskeleton organization

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000106988

P

Seeded From UniProt

complete

involved_in

GO:0071929

alpha-tubulin acetylation

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000106988

P

Seeded From UniProt

complete

enables

GO:0016746

transferase activity, transferring acyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0012

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Akella, JS et al. (2010) MEC-17 is an alpha-tubulin acetyltransferase. Nature 467 218-22 PubMed GONUTS page