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Contributes toGO:0045893positive regulation of transcription, DNA-templatedPMID:24598055IMP: Inferred from Mutant Phenotype P
This annotation made on page: MOUSE:STAT2
By: Drl5141 (group Team Protein Titans) on 2014-03-23 13:54:00 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeReadettd,
MichSt14A 19
2014-04-13 16:11:22 CDT

The qualifier contributes_to should only be used for molecular function annotations, and not biological process annotations.

1
Private
Assessment
Suzialeksander2014-05-12 16:58:17 CDTYou need to be an instructor to view these notes.Updated by Instructor
Private
Assessment
JimHu2014-04-21 18:39:28 CDTYou need to be an instructor to view these notes.Requires Changes
Go term
Public
Assessment
DanielRenfro2014-04-13 16:11:22 CDT

This annotation has been flagged because it has been edited since last assessment Contributes to||GO:0045893||positive regulation of transcription, DNA-templated||PMID:24598055||IMP: Inferred from Mutant Phenotype||||P||Upon INF alpha stimulation this protein STAT2 forms a heterodimer with STAT1 where upon it increases transcription of Three prime repair exonuclease 1 Trex1 this is demonstrated by knock out of Stat2 which did not have an increase in Trex1 expression with stimulation of IFN alpha. Similar events happened with knockout of STAT1, these were shown in figures 2 c and D along with Figure 4 C,D, and E. ||complete

Flagged
Private
Assessment
Suzialeksander2014-04-10 16:29:31 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Unique/Original