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GO:0016477cell migrationPMID:19255252IDA: Inferred from Direct Assay P
This annotation made on page: HUMAN:SMUF2
By: Cmpete (group Team Honey Badgers 14) on 2014-03-02 12:15:38 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeJack1034,
MichSt14A 38
2014-04-08 11:00:07 CDT

I suggest using the GO term, GO:1901165, which is positive regulation of trophoblast cell migration. Figure 2 supports this GO term because when Smurf2 is overexpressed, it enhanced the migration of HTR-8/SVneo cell, which are human invasive extravillous trophoblast (EVT) cell line. It shows that Smurf2 has a role in the migration of these cells.

2
ChallengeKatherine.thielen,
Team Just Name It Something
2014-03-13 15:01:13 CDT

I would suggest finding a new GO term. Smurf2 isn't necessarily a cell migrating protein, it just enhances it. Maybe find a GO term that supports the enhancement of cell migration, not migration itself.

1
Private
Assessment
Suzialeksander2014-05-09 16:14:47 CDTYou need to be an instructor to view these notes.Updated by Instructor
Public
Assessment
Briddle242014-04-13 16:50:51 CDT

Jack1034 earns credit for the corrected annotation.

Corrected Through Challenges
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2014-04-08 11:00:07 CDT

This annotation has been flagged because it has been edited since last assessment ||GO:0016477||cell migration||PMID:19255252||IDA: Inferred from Direct Assay||||P||Over-expression of Smurf2 enhanced the migration and invasion of HTR-8/SVneo Cells, Figure 2.||complete

Flagged
Private
Assessment
Suzialeksander2014-03-17 16:04:16 CDTYou need to be an instructor to view these notes.Requires Changes
Public
Assessment
DanielRenfro2014-03-13 15:01:13 CDT

This annotation has been flagged because it has been edited since last assessment ||GO:0016477||cell migration||PMID:19255252||IDA: Inferred from Direct Assay||||P||Over-expression of Smurf2 enhanced the migration and invasion of HTR-8/SVneo Cells, Figure 2.||complete

Flagged
Private
Assessment
Amcmillan2014-03-04 20:11:03 CSTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence