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GO:0006525arginine metabolic processPMID:9931298IMP: Inferred from Mutant Phenotype P
This annotation made on page: BIFAP:K4IP48
By: John.p.schmidt (group The A Team) on 2014-03-01 13:57:17 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeWiestcar,
MichSt14A 53
2014-04-11 09:44:47 CDT

The GO term for this would be better suited to be something similar to GO:0034618. Based on the article, it does not say that there are chemical reactions with arginine but rather when it interacts with the substrate it becomes active. When the residue becomes mutated, this activity stops.

I think the evidence code should remain IMP because it says that when the residue is mutated to have lysine, alanine, or tryptophan, there is no activity occurring showing that the arginine residue must be present to start the anchoring of the substrate.

0
ChallengeMin.lorna,
Team Texas Aggies
2014-03-05 01:07:50 CST

UniProt: P96789

2
Private
Assessment
Suzialeksander2014-05-23 16:11:27 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Private
Assessment
Suzialeksander2014-05-23 16:11:05 CDTYou need to be an instructor to view these notes.Updated by Instructor
Private
Assessment
Briddle242014-04-13 16:46:34 CDTYou need to be an instructor to view these notes.Requires Changes
Go term
Evidence
Notes
Public
Assessment
DanielRenfro2014-04-11 09:44:47 CDT

This annotation has been flagged because it has been edited since last assessment ||GO:0006525||arginine metabolic process||PMID:9931298||IMP: Inferred from Mutant Phenotype||||P||See page 57, "The role of the L. lactis 6-PGDH Arg-447 in binding substrate" paragraph, of associated PMID ||complete

Flagged
Private
Assessment
Suzialeksander2014-03-05 15:28:16 CSTYou need to be an instructor to view these notes.Requires Changes
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2014-03-05 01:07:50 CST

This annotation has been flagged because it has been edited since last assessment ||GO:0006525||arginine metabolic process||PMID:9931298||IMP: Inferred from Mutant Phenotype||||P||See page 57, "The role of the L. lactis 6-PGDH Arg-447 in binding substrate" paragraph, of associated PMID ||complete

Flagged
Private
Assessment
Kathrynmartin2014-03-03 17:39:45 CSTYou need to be an instructor to view these notes.Unacceptable
Protein
Notes