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GO:0032648regulation of interferon-beta productionPMID:16698997IMP: Inferred from Mutant Phenotype P
This annotation made on page: EBOZM:VP35
By: Swhipple (group Team Breakfast Taco) on 2013-03-12 22:12:34 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeBailey.dye,
Team Chloroplast
2013-04-15 12:30:47 CDT

Wild-type VP35, R312A, and K309A inhibit the SeV-induced activation of an IFN-Beta promoter reporter plasmid. Therefore the Go term should be 32688, which is more specific and codes for the negative regulation of interferon-beta production that is evident in the inhibition of the wild-type.

5
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Assessment
Bmcintosh2013-06-22 13:40:57 CDTYou need to be an instructor to view these notes.Updated by Instructor
Protein
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JimHu2013-04-28 11:39:40 CDT

Suggested GO term is more specific and could be used. Alternatively, GO:0039501 suppression by virus of host type I interferon production could be used. Sourceforge item submitted to make GO:0039501 suppression by virus of host type I interferon production a child of GO:0032688_!_negative_regulation_of_interferon-beta_production

Corrected Through Challenges
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DanielRenfro2013-04-15 12:30:47 CDT

This annotation has been flagged because it has been edited since last assessment

Flagged
Private
Assessment
Suzialeksander2013-03-18 16:17:56 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
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Unique/Original