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GO:0016301kinase activityPMID:16166371IDA: Inferred from Direct Assay F
This annotation made on page: CAEEL:PMK1
By: Jtplaisted (group Team The Terminators) on 2013-03-04 09:15:48 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeJtplaisted,
Team The Terminators
2013-04-01 09:33:22 CDT

The GO term should be "GO:0004672 protein kinase activity"

0
ChallengeSabrinamoisan,
Team M Squared
2013-03-20 19:15:59 CDT

Evidence code should be IMP because the Serine residues were changed to Alanine and from this they were able to infer that PMK-1 phosphorylates SKN-1. the Go term should be GO:0042501 serine phosphorylation of STAT protein. Figure 3C shows that PMK-1 phosphorylates SKN-1 at Ser-74 and Ser-340. (SKN-1 induces phase II detoxification gene transcription (in abstract) therefore leading me to conclude it could be classified as a STAT protein).

2
ChallengeLfileccia,
Team Breakfast Taco
2013-03-18 10:46:33 CDT

The GO term should be GO:0004707 MAP kinase activity

3
ChallengeBennettv,
Team Viral Load Challengers
2013-03-17 18:52:32 CDT

The GO ID should be GO:0006468 protein phosphorylation. The notes should read: "figure 3 shows the phosphorylation of transcription factor SKN-1 by this protein."

0
Public
Assessment
Suzialeksander2014-11-05 13:26:36 CST

Move Annotation 6790 from WB:pmk-1 to CAEEL:PMK1

Updated by Instructor
Private
Assessment
Bmcintosh2013-06-22 16:00:23 CDTYou need to be an instructor to view these notes.Updated by Instructor
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Private
Assessment
Bmcintosh2013-04-09 15:06:49 CDTYou need to be an instructor to view these notes.Corrected Through Challenges
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
JimHu2013-04-02 18:03:07 CDT

The change in GO term to GO:0004707 ! MAP kinase activity is actually adequate to fix this annotation. Although an IMP could be argued for from the active site mutation in Fig 3, the lanes doing the assay plus and minus the wt protein would be adequate to do this annotation as an IDA.

Corrected Through Challenges
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2013-04-01 09:33:22 CDT

This annotation has been flagged because it has been edited since last assessment

Flagged
Private
Assessment
Michael.torano2013-03-21 12:53:25 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2013-03-20 19:15:59 CDT

This annotation has been flagged because it has been edited since last assessment

Flagged
Private
Assessment
Bmcintosh2013-03-18 12:16:26 CDTYou need to be an instructor to view these notes.Requires Changes
Go term
Evidence
Public
Assessment
DanielRenfro2013-03-18 10:46:33 CDT

This annotation has been flagged because it has been edited since last assessment

Flagged
Private
Assessment
Bmcintosh2013-03-18 10:10:55 CDTYou need to be an instructor to view these notes.Requires Changes
Go term
Public
Assessment
DanielRenfro2013-03-17 18:52:32 CDT

This annotation has been flagged because it has been edited since last assessment

Flagged
Private
Assessment
Bmcintosh2013-03-06 22:51:30 CSTYou need to be an instructor to view these notes.Requires Changes
Go term