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GO:0000079regulation of cyclin-dependent protein kinase activityPMID:22927438IMP: Inferred from Mutant Phenotype P
This annotation made on page: DANRE:B3DHL9
By: Samtaylor (group Team Gene Simmons) on 2012-11-04 17:50:28 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeCbice1,
Team Smarter Who?
2012-11-07 10:25:31 CST

The discussion of figure 6B says "Among the non-responsive genes are the protein kinase genes erk2, her4, jnk.," and "By contrast, the expression of three genes (N-cadherin, p21, p27) was up-regulated ... The products of p21 and p27 are known for their function as cyclin-dependent kinase inhibitors" So there is no evidence of regulation of protein kinases in this figure. Additionally, I don't think qPCR shows regulation of a protein's activity; it shows regulation of gene expression, so the GO term is wrong for a couple reasons.

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Suzialeksander2012-11-27 19:45:38 CSTYou need to be an instructor to view these notes.Acceptable
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Bmcintosh2012-11-12 09:03:48 CSTYou need to be an instructor to view these notes.Requires Changes