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DANRE:B3DHL9
Contents
| Species (Taxon ID) | Danio rerio (Zebrafish) (Brachydanio rerio). (7955) | |
| Gene Name(s) | kcnh1a (ECO:0000313 with ZFIN:ZDB-GENE-061226-1) | |
| Protein Name(s) | Potassium voltage-gated channel, subfamily H (Eag-related), member 1 (ECO:0000313 with EMBL:AAI62812.1) | |
| External Links | ||
| UniProt | B3DHL9 | |
| EMBL | BC162812 | |
| UniGene | Dr.30012 | |
| ProteinModelPortal | B3DHL9 | |
| STRING | 7955.ENSDARP00000031629 | |
| ZFIN | ZDB-GENE-061226-1 | |
| eggNOG | COG2202 | |
| HOGENOM | HOG000230794 | |
| HOVERGEN | HBG101348 | |
| GO | GO:0016021 GO:0000155 GO:0005249 | |
| Gene3D | 2.60.120.10 | |
| InterPro | IPR018490 IPR000595 IPR030170 IPR005821 IPR003949 IPR003938 IPR001610 IPR000014 IPR000700 IPR014710 | |
| PANTHER | PTHR10217:SF377 | |
| Pfam | PF00027 PF00520 PF13426 | |
| PRINTS | PR01463 PR01464 | |
| SMART | SM00100 SM00086 SM00091 | |
| SUPFAM | SSF51206 SSF55785 | |
| TIGRFAMs | TIGR00229 | |
| PROSITE | PS50042 PS50113 PS50112 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0006355 |
regulation of transcription, DNA-dependent |
ECO:0000315 |
P |
Figure 6B shows early gene expression is modulated by kcnh1 following transcription. |
complete | |||||
| GO:0005249 |
voltage-gated potassium channel activity |
ECO:0000314 |
F |
Figure 2 shows that when expressed in Xenopus oocytes, kcnh1 responds to applied voltage and allows a potassium ion current to flow. |
complete | |||||
| GO:0007498 |
mesoderm development |
ECO:0000315 |
P |
Figure 6A shows reduced mesoderm in mutants |
complete | |||||
| GO:0010467 |
gene expression |
ECO:0000315 |
P |
Figure 6b shows alterations in the levels of gene expression. |
complete | |||||
|
involved_in |
GO:0007498 |
mesoderm development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005249 |
voltage-gated potassium channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043009 |
chordate embryonic development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-121127-4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0021576 |
hindbrain formation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-121127-4 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005249 |
voltage-gated potassium channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001756 |
somitogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-121127-4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0071805 |
potassium ion transmembrane transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1341721 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042391 |
regulation of membrane potential |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1341722 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1341721 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005249 |
voltage-gated potassium channel activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000535 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005216 |
ion channel activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005249 |
voltage-gated potassium channel activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006811 |
ion transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006813 |
potassium ion transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055085 |
transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071805 |
potassium ion transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034765 |
regulation of ion transmembrane transport |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006813 |
potassium ion transport |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005267 |
potassium channel activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071805 |
potassium ion transmembrane transport |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006811 |
ion transport |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005244 |
voltage-gated ion channel activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Stengel, R et al. (2012) Kcnh1 voltage-gated potassium channels are essential for early zebrafish development. J. Biol. Chem. 287 35565-75 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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